NFATc1 | Immunoglobe 0102-05 product information

product summary

company name :

Immunoglobe

product type :

antibody

product name :

NFATc1

catalog :

0102-05

quantity :

100 µl, 50 µg

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunoprecipitation

more info or order :

Immunoglobe product webpage

citations: 9

Reference
Glazova M, Aho T, Palmetshofer A, Murashov A, Scheinin M, Koskinen P. Pim-1 kinase enhances NFATc activity and neuroendocrine functions in PC12 cells. Brain Res Mol Brain Res. 2005;138:116-23 pubmed
Bhattacharyya S, Deb J, Patra A, Thuy Pham D, Chen W, Vaeth M, et al. NFATc1 affects mouse splenic B cell function by controlling the calcineurin--NFAT signaling network. J Exp Med. 2011;208:823-39 pubmed publisher
Klein M, Klein-Hessling S, Palmetshofer A, Serfling E, Tertilt C, Bopp T, et al. Specific and redundant roles for NFAT transcription factors in the expression of mast cell-derived cytokines. J Immunol. 2006;177:6667-74 pubmed
Klein-Hessling S, Bopp T, Jha M, Schmidt A, Miyatake S, Schmitt E, et al. Cyclic AMP-induced chromatin changes support the NFATc-mediated recruitment of GATA-3 to the interleukin 5 promoter. J Biol Chem. 2008;283:31030-7 pubmed publisher
Akimzhanov A, Krenacs L, Schlegel T, Klein-Hessling S, Bagdi E, Stelkovics E, et al. Epigenetic changes and suppression of the nuclear factor of activated T cell 1 (NFATC1) promoter in human lymphomas with defects in immunoreceptor signaling. Am J Pathol. 2008;172:215-24 pubmed
Patra A, Avots A, Zahedi R, Schüler T, Sickmann A, Bommhardt U, et al. An alternative NFAT-activation pathway mediated by IL-7 is critical for early thymocyte development. Nat Immunol. 2013;14:127-35 pubmed publisher
Silbermann K, Schneider G, Grassmann R. Stimulation of interleukin-13 expression by human T-cell leukemia virus type 1 oncoprotein Tax via a dually active promoter element responsive to NF-kappaB and NFAT. J Gen Virol. 2008;89:2788-98 pubmed publisher
Nayak A, Glöckner-Pagel J, Vaeth M, Schumann J, Buttmann M, Bopp T, et al. Sumoylation of the transcription factor NFATc1 leads to its subnuclear relocalization and interleukin-2 repression by histone deacetylase. J Biol Chem. 2009;284:10935-46 pubmed publisher
Hock M, Vaeth M, Rudolf R, Patra A, Pham D, Muhammad K, et al. NFATc1 induction in peripheral T and B lymphocytes. J Immunol. 2013;190:2345-53 pubmed publisher

product information

CATALOG NO :

0102-05

NAME (Link To Web Site) :

IG-205

SPECIFICITY :

NFATc1

OTHER NAMES :

NFATc1, NF-ATc, NF-ATc1, NFAT transcription complex cytosolic component, NFAT2, NFATc, Nuclear factor of activated T-cells c1, Nuclear factor of activated T-cells cytoplasmic 1

UniProt / Swiss-Prot # :

O95644, Q12865, Q15793

CLONE/Poly-clonal :

polyclonal

HOST SPECIES :

RABBIT

reactive species :

human

FORMAT/CONJUGATES :

affinity purified on the antigen

SIZE :

100 µl, 50 µg

DESCRIPTION :

antibody raised against recombinant protein (partial sequence); competes with probe for NFAT binding in band shift assays

APPLICATIONS :

WB - Western blot / immunoblot, IF - immunofluorescence, IHC - immuno-histochemistry, IP - immunoprecipitation, ChIP - chromatin immunoprecipitation

SUGGESTED DILUTIONS :

WB: (1:500-1:1,000); IP: (1:200), band shift assays

[PubMed-Id; PMID] :

18156209, 21464221, 15935514, 23365084, 17082579, 18772129, 19218564, 23263556, 18931077

Updated :

4/19/13

more info or order :

Immunoglobe product webpage