α-Actinin 4, alpha-Actinin 4 | Immunoglobe 0042-05 product information

product summary

company name :

Immunoglobe

product type :

antibody

product name :

α-Actinin 4, alpha-Actinin 4

catalog :

0042-05

quantity :

200 µl, 50 µg

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog, cow

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

Immunoglobe product webpage

citations: 8

Reference
Tomas N, Hoxha E, Reinicke A, Fester L, Helmchen U, Gerth J, et al. Autoantibodies against thrombospondin type 1 domain-containing 7A induce membranous nephropathy. J Clin Invest. 2016;126:2519-32 pubmed publisher
Foley K, Young P. An analysis of splicing, actin-binding properties, heterodimerization and molecular interactions of the non-muscle ?-actinins. Biochem J. 2013;452:477-88 pubmed publisher
Bhatnagar A, Unal H, Jagannathan R, Kaveti S, Duan Z, Yong S, et al. Interaction of G-protein ?? complex with chromatin modulates GPCR-dependent gene regulation. PLoS ONE. 2013;8:e52689 pubmed publisher
Jayadev R, Kuk C, Low S, Murata Hori M. Calcium sensitivity of ?-actinin is required for equatorial actin assembly during cytokinesis. Cell Cycle. 2012;11:1929-37 pubmed publisher
Meyer Schwesinger C, Dehde S, Klug P, Becker J, Mathey S, Arefi K, et al. Nephrotic syndrome and subepithelial deposits in a mouse model of immune-mediated anti-podocyte glomerulonephritis. J Immunol. 2011;187:3218-29 pubmed publisher
Meyer Schwesinger C, Meyer T, Sievert H, Hoxha E, Sachs M, Klupp E, et al. Ubiquitin C-terminal hydrolase-l1 activity induces polyubiquitin accumulation in podocytes and increases proteinuria in rat membranous nephropathy. Am J Pathol. 2011;178:2044-57 pubmed publisher
Hartleben B, Gödel M, Meyer Schwesinger C, Liu S, Ulrich T, Köbler S, et al. Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice. J Clin Invest. 2010;120:1084-96 pubmed publisher
Kumeta M, Yoshimura S, Harata M, Takeyasu K. Molecular mechanisms underlying nucleocytoplasmic shuttling of actinin-4. J Cell Sci. 2010;123:1020-30 pubmed publisher

product information

CATALOG NO :

0042-05

NAME (Link To Web Site) :

IG-701

SPECIFICITY :

α-Actinin 4, alpha-Actinin 4

OTHER NAMES :

α-Actinin 4, Actinin 4, ACTN4, alpha-Actinin 4

UniProt / Swiss-Prot # :

O43707, O76048, Q9QXQ0, Q6P786, P57780

CLONE/Poly-clonal :

polyclonal

HOST SPECIES :

RABBIT

reactive species :

tested: human, mouse, rat, pig, chinese hamster, marsupial (ptk2) by inference (sequence identity): dog, cow

FORMAT/CONJUGATES :

affinity purified on the antigen

SIZE :

200 µl, 50 µg

DESCRIPTION :

comes with a free positive control: human platelet protein (lysate); does not recognize closely related isoforms; works with formaldehyde fixed cells and tissues

APPLICATIONS :

IHC, immunofluorescence, immunoprecipitation, Western blots

SAMPLE APPLICATIONS :

IHC

SUGGESTED DILUTIONS :

WB 1:2,500, IF 1:250- 1:1,600, IP 1:10

[PubMed-Id; PMID] :

16943305, 23326349, 17336103, 16267652, 15031339, 20200449, 22544326, 18552466, 21844386, 21514420, 17925230, 18408146, 23557398, 20197409

Updated :

4/26/13

more info or order :

Immunoglobe product webpage