product summary
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company name :
Immunoglobe
product type :
antibody
product name :
Profilin
catalog :
0022-01
quantity :
100 µl, 10 µg
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, cow
application :
western blot
more info or order :
citations: 9
Reference
Peitsch W, Hofmann I, Grund C, Kuhn C, Moll I, Langbein L, et al. Drebrin particles: components in the ensemble of proteins regulating actin dynamics of lamellipodia and filopodia. Eur J Cell Biol. 2001;80:567-79 pubmed
Hauser W, Knobeloch K, Eigenthaler M, Gambaryan S, Krenn V, Geiger J, et al. Megakaryocyte hyperplasia and enhanced agonist-induced platelet activation in vasodilator-stimulated phosphoprotein knockout mice. Proc Natl Acad Sci U S A. 1999;96:8120-5 pubmed
Giesemann T, Rathke-Hartlieb S, Rothkegel M, Bartsch J, Buchmeier S, Jockusch B, et al. A role for polyproline motifs in the spinal muscular atrophy protein SMN. Profilins bind to and colocalize with smn in nuclear gems. J Biol Chem. 1999;274:37908-14 pubmed
Posern G, Miralles F, Guettler S, Treisman R. Mutant actins that stabilise F-actin use distinct mechanisms to activate the SRF coactivator MAL. EMBO J. 2004;23:3973-83 pubmed
Burns J, Kristiansen M, Kristensen L, Larsen K, Nielsen M, Christiansen H, et al. Decellularized matrix from tumorigenic human mesenchymal stem cells promotes neovascularization with galectin-1 dependent endothelial interaction. PLoS ONE. 2011;6:e21888 pubmed publisher
Rawe V, Payne C, Schatten G. Profilin and actin-related proteins regulate microfilament dynamics during early mammalian embryogenesis. Hum Reprod. 2006;21:1143-53 pubmed
Nikolova-Krstevski V, Leimena C, Xiao X, Kesteven S, Tan J, Yeo L, et al. Nesprin-1 and actin contribute to nuclear and cytoskeletal defects in lamin A/C-deficient cardiomyopathy. J Mol Cell Cardiol. 2011;50:479-86 pubmed publisher
Salazar R, Bell S, Davis G. Coordinate induction of the actin cytoskeletal regulatory proteins gelsolin, vasodilator-stimulated phosphoprotein, and profilin during capillary morphogenesis in vitro. Exp Cell Res. 1999;249:22-32 pubmed
Rawe V, Chemes H. Exploring the cytoskeleton during intracytoplasmic sperm injection in humans. Methods Mol Biol. 2009;518:189-206 pubmed publisher
product information
CATALOG NO :
0022-01
NAME (Link To Web Site) :
IG-706
SPECIFICITY :
Profilin
OTHER NAMES :
Profilin, ALS18, Amyotrophic lateral sclerosis 18, Epididymis tissue protein Li 184a, PFN1, Profilin (platelet), Profilin I, Profilin-1
UniProt / Swiss-Prot # :
P07737, Q53Y44
CLONE/Poly-clonal :
polyclonal
HOST SPECIES :
RABBIT
reactive species  :
human, mouse, rat, pig, bovine, marsupial (PtK2)
FORMAT/CONJUGATES :
affinity purified on the antigen
SIZE :
100 µl, 10 µg
DESCRIPTION :
comes with a free positive control: human platelet protein (lysate); antibody raised against full-length protein
APPLICATIONS :
WB - Western blot, immunoblot; IHC - immuno-histochemistry, ICC - immunocytochemistry, IF - immunofluorescence
SUGGESTED DILUTIONS :
WB 1:500 - 1:1,000
[PubMed-Id; PMID] :
21779348, 10608857, 10393958, 21156181, 11675932, 15385960, 16428331, 19085137, 16428331, 10328950
Updated :
5/6/13
more info or order :
company information
Immunoglobe
info@immunoGlobe.com
www.immunoglobe.com