product summary
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company name :
ImmunoStar
product type :
antibody
product name :
Glucagon Antibody
catalog :
20076
quantity :
100 µL
price :
210.00 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
immunohistochemistry, immunocytochemistry
more info or order :
citations: 48
Reference
Butler A, Campbell Thompson M, Gurlo T, Dawson D, Atkinson M, Butler P. Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors. Diabetes. 2013;62:2595-604 pubmed publisher
Fourcade G, Colombo B, Gregoire S, Baeyens A, Rachdi L, Guez F, et al. Fetal pancreas transplants are dependent on prolactin for their development and prevent type 1 diabetes in syngeneic but not allogeneic mice. Diabetes. 2013;62:1646-55 pubmed publisher
Kanji M, Martin M, Bhushan A. Dicer1 is required to repress neuronal fate during endocrine cell maturation. Diabetes. 2013;62:1602-11 pubmed publisher
Dhawan S, Georgia S, Tschen S, Fan G, Bhushan A. Pancreatic ? cell identity is maintained by DNA methylation-mediated repression of Arx. Dev Cell. 2011;20:419-29 pubmed publisher
Matveyenko A, Georgia S, Bhushan A, Butler P. Inconsistent formation and nonfunction of insulin-positive cells from pancreatic endoderm derived from human embryonic stem cells in athymic nude rats. Am J Physiol Endocrinol Metab. 2010;299:E713-20 pubmed publisher
Elson A, Dotson C, Egan J, Munger S. Glucagon signaling modulates sweet taste responsiveness. FASEB J. 2010;24:3960-9 pubmed publisher
Schulthess F, Paroni F, Sauter N, Shu L, Ribaux P, Haataja L, et al. CXCL10 impairs beta cell function and viability in diabetes through TLR4 signaling. Cell Metab. 2009;9:125-39 pubmed publisher
Scharfmann R, Xiao X, Heimberg H, Mallet J, Ravassard P. Beta cells within single human islets originate from multiple progenitors. PLoS ONE. 2008;3:e3559 pubmed publisher
Fontanière S, Duvillie B, Scharfmann R, Carreira C, Wang Z, Zhang C. Tumour suppressor menin is essential for development of the pancreatic endocrine cells. J Endocrinol. 2008;199:287-98 pubmed publisher
Gierl M, Karoulias N, Wende H, Strehle M, Birchmeier C. The zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells. Genes Dev. 2006;20:2465-78 pubmed
Georgia S, Soliz R, Li M, Zhang P, Bhushan A. p57 and Hes1 coordinate cell cycle exit with self-renewal of pancreatic progenitors. Dev Biol. 2006;298:22-31 pubmed
Matveyenko A, Butler P. Beta-cell deficit due to increased apoptosis in the human islet amyloid polypeptide transgenic (HIP) rat recapitulates the metabolic defects present in type 2 diabetes. Diabetes. 2006;55:2106-14 pubmed
Meier J, Lin J, Butler A, Galasso R, Martinez D, Butler P. Direct evidence of attempted beta cell regeneration in an 89-year-old patient with recent-onset type 1 diabetes. Diabetologia. 2006;49:1838-44 pubmed
Le May C, Chu K, Hu M, Ortega C, Simpson E, Korach K, et al. Estrogens protect pancreatic beta-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice. Proc Natl Acad Sci U S A. 2006;103:9232-7 pubmed
Ku S, Lee H. An immunohistochemical study of the pancreatic endocrine cells of the nude mouse, Balb/c-nu/nu. Eur J Histochem. 2006;50:61-8 pubmed
Meier J, Kjems L, Veldhuis J, Lefebvre P, Butler P. Postprandial suppression of glucagon secretion depends on intact pulsatile insulin secretion: further evidence for the intraislet insulin hypothesis. Diabetes. 2006;55:1051-6 pubmed
Kim J, Kang S, Seo B, Choi H, Choi H, Ku S. Anti-diabetic activity of SMK001, a poly herbal formula in streptozotocin induced diabetic rats: therapeutic study. Biol Pharm Bull. 2006;29:477-82 pubmed
Castaing M, Duvillie B, Quemeneur E, Basmaciogullari A, Scharfmann R. Ex vivo analysis of acinar and endocrine cell development in the human embryonic pancreas. Dev Dyn. 2005;234:339-45 pubmed
Ku S, Lee H. Distribution and frequency of endocrine cells in the pancreas of the ddY mouse: an immunohistochemical study. Eur J Histochem. 2005;49:125-30 pubmed
Wang G, Yao J, Worah S, White J, Luna R, Wu T, et al. Comparison of genetic alterations in neuroendocrine tumors: frequent loss of chromosome 18 in ileal carcinoid tumors. Mod Pathol. 2005;18:1079-87 pubmed
Ku S, Lee H, Byun J, Seo B, Lee J. Changes of the gastric endocrine cells in the C57BL/6 mouse after implantation of murine lung carcinoma: an immunohistochemical quantitative study. World J Gastroenterol. 2005;11:1317-23 pubmed
Ku S, Lee H, Lee J. Immunohistochemical study of the pancreatic endocrine cells in the BALB/c mice: an unique distributional pattern of glucagon. J Vet Sci. 2002;3:167-73 pubmed
Rachdi L, Marie J, Scharfmann R. Role for VPAC2 receptor-mediated signals in pancreas development. Diabetes. 2003;52:85-92 pubmed
True L, Buhler K, Quinn J, Williams E, Nelson P, Clegg N, et al. A neuroendocrine/small cell prostate carcinoma xenograft-LuCaP 49. Am J Pathol. 2002;161:705-15 pubmed
Elghazi L, Cras Méneur C, Czernichow P, Scharfmann R. Role for FGFR2IIIb-mediated signals in controlling pancreatic endocrine progenitor cell proliferation. Proc Natl Acad Sci U S A. 2002;99:3884-9 pubmed
Huang H, Chu K, Nemoz Gaillard E, Elberg D, Tsai M. Neogenesis of beta-cells in adult BETA2/NeuroD-deficient mice. Mol Endocrinol. 2002;16:541-51 pubmed
Yang Q, Bermingham N, Finegold M, Zoghbi H. Requirement of Math1 for secretory cell lineage commitment in the mouse intestine. Science. 2001;294:2155-8 pubmed
Cras Méneur C, Elghazi L, Czernichow P, Scharfmann R. Epidermal growth factor increases undifferentiated pancreatic embryonic cells in vitro: a balance between proliferation and differentiation. Diabetes. 2001;50:1571-9 pubmed
Mitra S, Mezey E, Hunyady B, Chamberlain L, Hayes E, Foor F, et al. Colocalization of somatostatin receptor sst5 and insulin in rat pancreatic beta-cells. Endocrinology. 1999;140:3790-6 pubmed
Park I, Che Y, Bendayan M, Kang S, Min B. Up-regulation of clusterin (sulfated glycoprotein-2) in pancreatic islet cells upon streptozotocin injection to rats. J Endocrinol. 1999;162:57-65 pubmed
Komatsu S, Yamamoto M, Arishima K, Eguchi Y. Maternal adrenocortical hormones maintain the early development of pancreatic B cells in the fetal rat. J Anat. 1998;193 ( Pt 4):551-7 pubmed
Dheen S, Rajkumar K, Murphy L. Islet cell proliferation and apoptosis in insulin-like growth factor binding protein-1 in transgenic mice. J Endocrinol. 1997;155:551-8 pubmed
Wetzel R, Eldred W. Specialized neuropeptide Y- and glucagon-like immunoreactive amacrine cells in the peripheral retina of the turtle. Vis Neurosci. 1997;14:867-77 pubmed
Naya F, Huang H, Qiu Y, Mutoh H, DeMayo F, Leiter A, et al. Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice. Genes Dev. 1997;11:2323-34 pubmed
Stellrecht C, DeMayo F, Finegold M, Tsai M. Tissue-specific and developmental regulation of the rat insulin II gene enhancer, RIPE3, in transgenic mice. J Biol Chem. 1997;272:3567-72 pubmed
Sugitani A, Reynolds J, Todo S. Immunohistochemical study of enteric nervous system after small bowel transplantation in humans. Dig Dis Sci. 1994;39:2448-56 pubmed
Pang K, Mukonoweshuro C, Wong G. Beta cells arise from glucose transporter type 2 (Glut2)-expressing epithelial cells of the developing rat pancreas. Proc Natl Acad Sci U S A. 1994;91:9559-63 pubmed
Watanabe T, Chikazawa H, Yamada J. Catecholamine-containing pancreatic islet cells of the domestic fowl. Light, fluorescence and electron microscopy, and immunohistochemistry. Cell Tissue Res. 1984;237:239-44 pubmed
Cohn D, Elting J, Frick M, Elde R. Selective localization of the parathyroid secretory protein-I/adrenal medulla chromogranin A protein family in a wide variety of endocrine cells of the rat. Endocrinology. 1984;114:1963-74 pubmed
Rawdon B, Andrew A. An immunocytochemical survey of endocrine cells in the gastrointestinal tract of chicks at hatching. Cell Tissue Res. 1981;220:279-92 pubmed
Davidson M, Harris M, Ziel F, Rosenberg C. Suppression of sleep-induced growth hormone secretion by anticholinergic agent abolishes dawn phenomenon. Diabetes. 1988;37:166-71 pubmed
Buchan A, Gregor M, Riecken E. Immunocytochemical characterization of glucagon-immunoreactive cells using monoclonal antibodies to pancreatic glucagon. Histochemistry. 1987;87:79-83 pubmed
Seglen P, Skomedal H, Saeter G, Schwarze P, Nesland J. Neuroendocrine dysdifferentiation and bombesin production in carcinogen-induced hepatocellular rat tumours. Carcinogenesis. 1989;10:21-5 pubmed
Sithigorngul P, Stretton A, Cowden C. Neuropeptide diversity in Ascaris: an immunocytochemical study. J Comp Neurol. 1990;294:362-76 pubmed
Pak C, Cha C, Rajotte R, McArthur R, Yoon J. Human pancreatic islet cell specific 38 kilodalton autoantigen identified by cytomegalovirus-induced monoclonal islet cell autoantibody. Diabetologia. 1990;33:569-72 pubmed
Honkanen T, Ekstrom P. An immunocytochemical study of the development of the olfactory system in the three-spined stickleback (Gasterosteus aculeatus L., Teleostei). Anat Embryol (Berl). 1991;184:469-77 pubmed
Elliott W, Youson J. Somatostatin concentrations in the pancreatic-intestinal tissues of the sea lamprey, Petromyzon marinus L., at various periods of its life cycle. Comp Biochem Physiol A Comp Physiol. 1991;99:357-60 pubmed
Ding W, Fujimura M, Tooyama I, Kimura H. Phylogenetic study of serotonin-immunoreactive structures in the pancreas of various vertebrates. Cell Tissue Res. 1991;263:237-43 pubmed
image
image 1 :
ImmunoStar 20076 image 1
Immunohistochemical image of alpha cells in the islets of Langerhans of the rat pancreas staining for glucagon (1) and counterstained with hemotoxylin (2).
product information
Catalog # :
20076
Product Name :
Glucagon Antibody
Product Type :
Antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Size :
100 µL
PRICE :
210.00 USD
CrossReactivity :
Chick, Human, Mouse, Pig, Rat, Sea Lamprey, Snail, Three-Spined Stickleback (Fish), Turtle
Immunogen :
Glucagon
Applications :
Used in Electron Microscopy; Immunocytochemistry; Immunofluorescence; Immunohistochemistry.
Format - which column? :
Whole Serum
more info or order :
company information
ImmunoStar
P.O. Box 488
Hudson, WI 54016-0488
info@immunostar.com
http://www.immunostar.com
1-866-386-3500
headquarters: USA