product summary
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company name :
ImmunoStar
product type :
antibody
product name :
Insulin Antibody
catalog :
20056
quantity :
100 µL
price :
210.00 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
more info or order :
citations: 45
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; human; 1:1000
Nicol L, O Brien T, Dumesic D, Grogan T, Tarantal A, Abbott D. Abnormal infant islet morphology precedes insulin resistance in PCOS-like monkeys. PLoS ONE. 2014;9:e106527 pubmed publisher
Nicol L, Grant W, Grant W, Comstock S, Nguyen M, Smith M, et al. Pancreatic inflammation and increased islet macrophages in insulin-resistant juvenile primates. J Endocrinol. 2013;217:207-13 pubmed publisher
Jung H, Jung J, Ramalingam M, Yoon C, Bae H, Park Y. Anti-diabetic effect of Wen-pi-tang-Hab-Wu-ling-san extract in streptozotocin-induced diabetic rats. Indian J Pharmacol. 2012;44:97-102 pubmed publisher
Danilova O, Tai A, Mele D, Beinborn M, Leiter A, Greenberg A, et al. Neurogenin 3-specific dipeptidyl peptidase-2 deficiency causes impaired glucose tolerance, insulin resistance, and visceral obesity. Endocrinology. 2009;150:5240-8 pubmed publisher
Du Y, Klimstra D, Varmus H. Activation of PyMT in beta cells induces irreversible hyperplasia, but oncogene-dependent acinar cell carcinomas when activated in pancreatic progenitors. PLoS ONE. 2009;4:e6932 pubmed publisher
Heart E, Cline G, Collis L, Pongratz R, Gray J, Smith P. Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion. Am J Physiol Endocrinol Metab. 2009;296:E1354-62 pubmed publisher
Ravassard P, Emilie Bricout Neveu -, Hazhouz Y, Pechberty S, Mallet J, Czernichow P, et al. A new strategy to generate functional insulin-producing cell lines by somatic gene transfer into pancreatic progenitors. PLoS ONE. 2009;4:e4731 pubmed publisher
Hasegawa G, Fukui M, Hosoda H, Asano M, Harusato I, Tanaka M, et al. Telmisartan, an angiotensin II type 1 receptor blocker, prevents the development of diabetes in male Spontaneously Diabetic Torii rats. Eur J Pharmacol. 2009;605:164-9 pubmed publisher
Lacroix M, Badonnel K, Meunier N, Tan F, Schlegel Le Poupon C, Durieux D, et al. Expression of insulin system in the olfactory epithelium: first approaches to its role and regulation. J Neuroendocrinol. 2008;20:1176-90 pubmed publisher
Du Y, Lewis B, Hanahan D, Varmus H. Assessing tumor progression factors by somatic gene transfer into a mouse model: Bcl-xL promotes islet tumor cell invasion. PLoS Biol. 2007;5:e276 pubmed
Duvillie B, Heinis M, Stetsyuk V. In vivo and in vitro techniques to study pancreas development and islet cell function. Endocr Dev. 2007;12:46-54 pubmed
Yasuda M, Yamamoto M, Ochiai H, Eguchi Y, Arishima K. Effects of growth factors on development of fetal islet B-cells in vitro. J Vet Med Sci. 2007;69:807-11 pubmed
Castaing M, Guerci A, Mallet J, Czernichow P, Ravassard P, Scharfmann R. Efficient restricted gene expression in beta cells by lentivirus-mediated gene transfer into pancreatic stem/progenitor cells. Diabetologia. 2005;48:709-19 pubmed
Ku S, Lee H. The distribution and frequency of endocrine cells in the splenic lobe of grass lizard (Takydromus wolteri). An immunohistochemical study. Eur J Histochem. 2004;48:429-36 pubmed
Zhang Q, Davenport J, Croyle M, Haycraft C, Yoder B. Disruption of IFT results in both exocrine and endocrine abnormalities in the pancreas of Tg737(orpk) mutant mice. Lab Invest. 2005;85:45-64 pubmed
Yamamoto M, Yasuda M, Hori A, Arishima K, Eguchi Y. Recovery in the fetal pancreatic islet following fetal administration of streptozotocin in the rat in vivo and in vitro. Anat Rec A Discov Mol Cell Evol Biol. 2004;281:1319-25 pubmed
Lewis B, Klimstra D, Varmus H. The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic cancer. Genes Dev. 2003;17:3127-38 pubmed
Duvillie B, Attali M, Aiello V, Quemeneur E, Scharfmann R. Label-retaining cells in the rat pancreas: location and differentiation potential in vitro. Diabetes. 2003;52:2035-42 pubmed
Ku S, Lee H, Lee J. Immunohistochemical study of the pancreatic endocrine cells in the BALB/c mice: an unique distributional pattern of glucagon. J Vet Sci. 2002;3:167-73 pubmed
Elghazi L, Cras Méneur C, Czernichow P, Scharfmann R. Role for FGFR2IIIb-mediated signals in controlling pancreatic endocrine progenitor cell proliferation. Proc Natl Acad Sci U S A. 2002;99:3884-9 pubmed
Page B, Du Toit D, Muller C, Mattysen J, Lyners R. An immunocytochemical profile of the endocrine pancreas using an occlusive duct ligation model. JOP. 2000;1:191-203 pubmed
Pin C, Rukstalis J, Johnson C, Konieczny S. The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity. J Cell Biol. 2001;155:519-30 pubmed
Baltazar E, Kitamura N, Hondo E, Narreto E, Yamada J. Galanin-like immunoreactive endocrine cells in bovine pancreas. J Anat. 2000;196 ( Pt 2):285-91 pubmed
Hoshida S, Yamashita N, Otsu K, Kuzuya T, Hori M. Cholesterol feeding exacerbates myocardial injury in Zucker diabetic fatty rats. Am J Physiol Heart Circ Physiol. 2000;278:H256-62 pubmed
Mitra S, Mezey E, Hunyady B, Chamberlain L, Hayes E, Foor F, et al. Colocalization of somatostatin receptor sst5 and insulin in rat pancreatic beta-cells. Endocrinology. 1999;140:3790-6 pubmed
Usdin T, Hilton J, Vertesi T, Harta G, Segre G, Mezey E. Distribution of the parathyroid hormone 2 receptor in rat: immunolocalization reveals expression by several endocrine cells. Endocrinology. 1999;140:3363-71 pubmed
Komatsu S, Yamamoto M, Arishima K, Eguchi Y. Maternal adrenocortical hormones maintain the early development of pancreatic B cells in the fetal rat. J Anat. 1998;193 ( Pt 4):551-7 pubmed
Lucini C, Castaldo L, Lai O, De Vico G. Ontogeny, postnatal development and ageing of endocrine pancreas in Bubalus bubalis. J Anat. 1998;192 ( Pt 3):417-24 pubmed
Rosenbaum T, Vidaltamayo R, Sánchez Soto M, Zentella A, Hiriart M. Pancreatic beta cells synthesize and secrete nerve growth factor. Proc Natl Acad Sci U S A. 1998;95:7784-8 pubmed
Dheen S, Rajkumar K, Murphy L. Islet cell proliferation and apoptosis in insulin-like growth factor binding protein-1 in transgenic mice. J Endocrinol. 1997;155:551-8 pubmed
Kim S, Hebrok M, Melton D. Notochord to endoderm signaling is required for pancreas development. Development. 1997;124:4243-52 pubmed
Naya F, Huang H, Qiu Y, Mutoh H, DeMayo F, Leiter A, et al. Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice. Genes Dev. 1997;11:2323-34 pubmed
Stellrecht C, DeMayo F, Finegold M, Tsai M. Tissue-specific and developmental regulation of the rat insulin II gene enhancer, RIPE3, in transgenic mice. J Biol Chem. 1997;272:3567-72 pubmed
Lipes M, Cooper E, Skelly R, Rhodes C, Boschetti E, Weir G, et al. Insulin-secreting non-islet cells are resistant to autoimmune destruction. Proc Natl Acad Sci U S A. 1996;93:8595-600 pubmed
Pang K, Mukonoweshuro C, Wong G. Beta cells arise from glucose transporter type 2 (Glut2)-expressing epithelial cells of the developing rat pancreas. Proc Natl Acad Sci U S A. 1994;91:9559-63 pubmed
Taniyama H, Ushiki T, Tajima M, Kurosawa T, Kitamura N, Takahashi K, et al. Spontaneous diabetes mellitus associated with persistent bovine viral diarrhea (BVD) virus infection in young cattle. Vet Pathol. 1995;32:221-9 pubmed
Oomori Y, Iuchi H, Ishikawa K, Satoh Y, Ono K. Immunocytochemical study of tyrosine hydroxylase and dopamine beta-hydroxylase immunoreactivities in the rat pancreas. Histochemistry. 1994;101:313-23 pubmed
Cohn D, Elting J, Frick M, Elde R. Selective localization of the parathyroid secretory protein-I/adrenal medulla chromogranin A protein family in a wide variety of endocrine cells of the rat. Endocrinology. 1984;114:1963-74 pubmed
Dunn P, Sheppard M, Heath D, Slaney G. Recurrent insulinoma syndrome with metastatic glucagonoma. J Clin Pathol. 1983;36:1076-80 pubmed
Bhathena S, Aparicio P, Revett K, Voyles N, Recant L. Effect of dietary carbohydrates on glucagon and insulin receptors in genetically obese female Zucker rats. J Nutr. 1987;117:1291-7 pubmed
Sithigorngul P, Stretton A, Cowden C. Neuropeptide diversity in Ascaris: an immunocytochemical study. J Comp Neurol. 1990;294:362-76 pubmed
Homberg U, Davis N, Hildebrand J. Peptide-immunocytochemistry of neurosecretory cells in the brain and retrocerebral complex of the sphinx moth Manduca sexta. J Comp Neurol. 1991;303:35-52 pubmed
Smith S, Prior R, Koong L, Mersmann H. Nitrogen and lipid metabolism in heifers fed at increasing levels of intake. J Anim Sci. 1992;70:152-60 pubmed
Tay S, Wong W. Insulin-like immunoreactivity in the monkey spinal cord. Acta Anat (Basel). 1992;144:196-201 pubmed
Vittoria A, Cocca T, La Mura E, Cecio A. Immunocytochemistry of paraneurons in the female urethra of the horse, cattle, sheep, and pig. Anat Rec. 1992;233:18-24 pubmed
image
image 1 :
ImmunoStar 20056 image 1
Immunohistochemical image of beta cells in the islets of Langerhans of the rat pancreas staining for insulin (1) and counterstained with hemotoxylin (2).
product information
Catalog # :
20056
Product Name :
Insulin Antibody
Product Type :
Antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Size :
100 µL
PRICE :
210.00 USD
CrossReactivity :
Bubalus Bubalis (Buffalo), Cattle, Chick, Cow, Heifer (Cow), Horse, Human, Lizard, Macaque, Manducta Sexta (Moth), Monkey, Mouse, Pig, Rat, Sheep
Immunogen :
Insulin
Applications :
Used in Electron Microscopy; Immunocytochemistry; Immunofluorescence; Immunohistochemistry.
Format - which column? :
Whole Serum
more info or order :
company information
ImmunoStar
P.O. Box 488
Hudson, WI 54016-0488
info@immunostar.com
http://www.immunostar.com
1-866-386-3500
headquarters: USA