Amyloidβ (1-43) Anti-Human Rabbit IgG Affinity Purify | Immuno-Biological Laboratories 18583 product information

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product summary

company name :

Immuno-Biological Laboratories

product type :

antibody

product name :

Amyloidβ (1-43) Anti-Human Rabbit IgG Affinity Purify

catalog :

18583

quantity :

50 µg

price :

499 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry

product information

Catalog Number :

18583

Item Name :

Amyloidβ (1-43) Anti-Human Rabbit IgG Affinity Purify

Description :

Alzheimer's disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein component of these plaques is beta amyloid (Aβ) peptide, a 40 to 43 amino acid peptide cleaved from amyloid precursor protein by β-secretase and γ-secretase. Increased release of Aβ42 or Aβ43, both of which exibit a greater tendency to aggregate than Aβ40, occurs in individuals expressing certain genetic mutations, ApoE alleles or may involve other undiscovered factors. Many researchers theorize that it is this increased release of Aβ42/Aβ43 which leads to the abnormal deposition of Aβ and the associated neurotoxicity in the brains of affected individuals.

Anti-Species :

Anti-Human

Host :

Rabbit

Applications :

IHC, WB.

Antibody Type :

Polyclonal

Immunogen :

Synthetic peptide of the C terminal part of Human Amyloidβ43.

Synonyms :

Amyloid beta, A-beta, Aβ.

Purification :

Purified with antigen peptide.

Specificity :

Human Amyloidβ43 specific. Doesnâ€™t cross-react with human Amyloidβ40 or 42.

Storage :

Lyophilized product, 5 years at 2 - 8°C; Solution, 2 years at -20°C.

Formulation :

Lyophilized product from PBS containing 1 % BSA and 0.05 % NaN3.

Size :

50 µg

List Price :

499 USD

Notes :

For research use only, not for use in diagnostic procedures.