sAPP-Beta-sw (6A1) Anti-Human Mouse IgG MoAb | Immuno-Biological Laboratories 10321 product information

product summary

company name :

Immuno-Biological Laboratories

product type :

antibody

product name :

sAPP-Beta-sw (6A1) Anti-Human Mouse IgG MoAb

catalog :

10321

quantity :

100 μg

price :

499 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6A1

reactivity :

human, mouse

application :

western blot

more info or order :

Immuno-Biological Laboratories product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; loading ...; fig 3e	Li J, Chiu J, Ramanjulu M, Blass B, Pratico D. A pharmacological chaperone improves memory by reducing Aβ and tau neuropathology in a mouse model with plaques and tangles. Mol Neurodegener. 2020;15:1 pubmed publisher
western blot; mouse; 1:50; loading ...; fig 3e	Walter S, Jumpertz T, Hüttenrauch M, Ogorek I, Gerber H, Storck S, et al. The metalloprotease ADAMTS4 generates N-truncated Aβ4-x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer's disease. Acta Neuropathol. 2019;137:239-257 pubmed publisher
western blot; human; loading ...; fig 1c	Mukadam A, Breusegem S, Seaman M. Analysis of novel endosome-to-Golgi retrieval genes reveals a role for PLD3 in regulating endosomal protein sorting and amyloid precursor protein processing. Cell Mol Life Sci. 2018;75:2613-2625 pubmed publisher
western blot; mouse; 1:500; loading ...; fig 4a	Yan L, Deng Y, Gao J, Liu Y, Li F, Shi J, et al. Icariside II Effectively Reduces Spatial Learning and Memory Impairments in Alzheimer's Disease Model Mice Targeting Beta-Amyloid Production. Front Pharmacol. 2017;8:106 pubmed publisher
western blot; human; 1:250; loading ...; fig 8	Salta E, Sierksma A, Vanden Eynden E, De Strooper B. miR-132 loss de-represses ITPKB and aggravates amyloid and TAU pathology in Alzheimer's brain. EMBO Mol Med. 2016;8:1005-18 pubmed publisher
	Suh J, Romano D, Nitschke L, Herrick S, DiMarzio B, Dzhala V, et al. Loss of Ataxin-1 Potentiates Alzheimer's Pathogenesis by Elevating Cerebral BACE1 Transcription. Cell. 2019;178:1159-1175.e17 pubmed publisher
	Kizuka Y, Kitazume S, Fujinawa R, Saito T, Iwata N, Saido T, et al. An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease. EMBO Mol Med. 2015;7:175-89 pubmed publisher

product information

Catalog Number :

10321

Item Name :

sAPP-Beta-sw (6A1) Anti-Human Mouse IgG MoAb

Description :

This antibody can be stained in sAPPβ-sw gene transfected COS cells after fixation by 20% formalin containing methanol solution without any pretreatment by several cytochemical techniques such as Avidin Biotin Complex (ABC) Method. On the other hand, the antibody can not stained sAPPβ-wild type gene transfected COS cells by same procedure. The optimal dilution is about 5μg/ml, however, the dilution rate should be optimized by each laboratories. This antibody can be used for western blotting in concentration of about 5μg /ml. This antibody can not be used for immuno-precipitation.

Anti-Species :

Anti-Human

Host :

Mouse

Clone Number :

6A1

Applications :

Antibody Type :

Monoclonal

Isotype :

IgG3

Immunogen :

Synthetic peptide for C-Terminal of Human sAPPβ-sw (ISEVNL)

Synonyms :

Soluble βAmyloid Precursor Protein -Swedish

Storage :

Lyophilized product, 5 years at 2 - 8 â„ƒ, Solution, 2 years at -20 â„ƒ

Formulation :

Lyophilized product from 1% BSA in PBS containing 0.05%NaN3

Size :

100 μg

List Price :

499 USD

Notes :

For research use only, not for use in diagnostic procedures.

more info or order :

Immuno-Biological Laboratories product webpage