p53 Antibody [PAb1801] | ImmuQuest IQ646 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ImmuQuest

product type :

antibody

product name :

p53 Antibody [PAb1801]

catalog :

IQ646

quantity :

0.1 ml

price :

345 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

'PAb1801

reactivity :

human, rat

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation, flow cytometry, radioimmunoassay, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

product information

Product Name :

p53 Antibody [PAb1801]

Target Antigen :

p53

Primary Description :

Mouse anti p53 [PAb1801]

Catalogue Number :

IQ646

Quantity :

0.1 ml

Concentration :

1mg/ml

Clone :

'PAb1801

Host :

Mouse

Isotype :

IgG1

Immunogen :

Purified p53-b-galactosidase fusion protein

Myeloma/fusion partners :

Cells from immunized Balb/c mice were fused with the NS1 myeloma cell line

Specificity :

This antibody recognises cellular tumour antigen p53, a 50kDa transcription factor and major tumour suppressor that plays a major role in regulating cellular responses to DNA damage and other genomic aberrations. Mutation of p53 is the most common genetic change so far identified in a number of major carcinomas. The Pab1801 antibody recognizes an epitope between amino acids 32 and 79 of both wild-type and mutant p53

Species Reactivity :

Rat, Human

Purification :

Purified on protein A from tissue culture supernatant.

Format :

Purified IgG supplied in Phosphate buffered saline (PBS) containing 0.09% Sodium azide

Applications :

ELISA, Flow cyt, ICC/IF, IHC-Fr, IHC-P, IP, RIA, WB

Dilutions :

Optimal antibody dilution should be determined by titration

References :

Banks L, et al. Isolation of human-p53-specific monoclonal antibodies and their use in the studies of human p53 expression. Eur J Biochem. 1986.159(3):529-34. PMID:2428616 http://www.ncbi.nlm.nih.gov/pubmed/2428616; Said JW, et al. Immunohistochemical analysis of p53 expression in malignant lymphomas. Am J Pathol. 1992.141(6):1343-8. PMID:1466398 http://www.ncbi.nlm.nih.gov/pubmed/1466398

Database links :

Entrez Gene: 7157 Human; Entrez Gene: 24842 Rat; Omim: 191170 Human; SwissProt: P04637 Human; SwissProt: P10361 Rat; Unigene: 654481 Human; Unigene: 54443 Rat

Research areas :

Epigenetics; Tumour supressor; Transcription

Also known as :

Antigen NY-CO-13; Cellular tumor antigen p53; FLJ92943; LFS1; P53; p53 antigen; p53 transformation suppressor; p53 tumor suppressor; Phosphoprotein p53; TP53; transformation-related protein 53; TRP53; tumor protein p53; Tumor suppressor p53

Price (Pounds) :

226

Price (Dollars) :

345 USD

Price (Euros) :

338