product summary
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company name :
ImmuQuest
product type :
antibody
product name :
MUC1 Antibody [SM3]: Fluorescein
catalog :
IQ636FITC
quantity :
50 ul
price :
380 USD
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
'SM3
reactivity :
human
application :
immunocytochemistry, flow cytometry
more info or order :
ImmuQuest product webpage
product information
Product Name :
MUC1 Antibody [SM3]: Fluorescein
Target Antigen :
MUC1
Primary Description :
Mouse anti MUC1 [SM3]: Fluorescein
Catalogue Number :
IQ636FITC
Quantity :
50 ul
Concentration :
1mg/ml
Clone :
'SM3
Host :
Mouse
Isotype :
IgG2a
Immunogen :
Hydrogen fluoride deglycosylated milk mucin.
Myeloma/fusion partners :
Cells from immunized Balb/c mice were fused with the NS2 myeloma cell line
Specificity :
This antibody recognises mucin 1 (MUC1). MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoitic cell lineages. In the vast majority of human carcinomas, this protein is upregulated, poorly glycosylated and appears on the cell surface in a non-polarised fashion. The SM3 antibody reacts with a core protein epitope defined as PDTRP. SM3 also detects MUC1 within colon and ovarian cancer and most adenocarcinomas.
Species Reactivity :
Human
Purification :
Purified on protein A from tissue culture supernatant.
Format :
Purified IgG conjugated to Fluoroscein using Innova Biosciences Lightning-Link®, supplied in Phosphate buffered saline (PBS) containing 0.09% Sodium azide
Applications :
Flow cyt, ICC/IF
Dilutions :
Optimal antibody dilution should be determined by titration
References :
Burchell J, et al. A short sequence, within the amino acid tandem repeat of a cancer-associated mucin, contains immunodominant epitopes. Int J Cancer.1989.44(4):691-6. PMID:2477336 http://www.ncbi.nlm.nih.gov/pubmed/2477336; Burchell J, et al. Development and characterization of breast cancer reactive monoclonal antibodies directed to the core protein of the human milk mucin. Cancer Res.1987. 47(20):5476-82. PMID:2443241 http://www.ncbi.nlm.nih.gov/pubmed/2443241
Database links :
Entrez Gene: 4582 Human; Omim: 158340 Human; SwissProt: P15941 Human; Unigene: 89603 Human
Research areas :
Epigenetics; DNA damage repair
Also known as :
Breast carcinoma-associated antigen DF3; Carcinoma-associated mucin; CD227; DF3 antigen; EMA; Episialin; H23 antigen; H23AG; KL-6; MAM6; MUC-1; MUC-1/SEC; MUC-1/X; MUC1; MUC1-alpha; MUC1-beta; MUC1-CT; MUC1-NT; MUC1/ZD; mucin 1, cell surface associated; mucin 1, transmembrane; Mucin-1; Mucin-1 subunit alpha; Mucin-1 subunit beta; Peanut-reactive urinary mucin; PEM; PEMT; Polymorphic epithelial mucin; PUM; tumor associated epithelial mucin; Tumor-associated epithelial membrane antigen; Tumor-associated mucin
Price (Pounds) :
245
Price (Dollars) :
380 USD
Price (Euros) :
366
more info or order :
ImmuQuest product webpage
company information
ImmuQuest
26 The Green
Seamer, N.Yorkshire
TS9 5LP
adam@immuquest.com
www.immuquest.com
44 0 1642-713533
headquarters: UK
Our QUEST is to work in partnership with the scientific community to deliver a unique and, wherever possible, exclusive range of quality antibodies for use in existing and emerging areas of scientific research.