MUC1 Antibody [SM3] | ImmuQuest IQ636 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ImmuQuest

product type :

antibody

product name :

MUC1 Antibody [SM3]

catalog :

IQ636

quantity :

0.1 ml

price :

345 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

'SM3

reactivity :

human

application :

immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

product information

Product Name :

MUC1 Antibody [SM3]

Target Antigen :

MUC1

Primary Description :

Mouse anti MUC1 [SM3]

Catalogue Number :

IQ636

Quantity :

0.1 ml

Concentration :

1mg/ml

Clone :

'SM3

Host :

Mouse

Isotype :

IgG2a

Immunogen :

Hydrogen fluoride deglycosylated milk mucin.

Myeloma/fusion partners :

Cells from immunized Balb/c mice were fused with the NS2 myeloma cell line

Specificity :

This antibody recognises mucin 1 (MUC1). MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoitic cell lineages. In the vast majority of human carcinomas, this protein is upregulated, poorly glycosylated and appears on the cell surface in a non-polarised fashion. The SM3 antibody reacts with a core protein epitope defined as PDTRP. SM3 also detects MUC1 within colon and ovarian cancer and most adenocarcinomas.

Species Reactivity :

Human

Purification :

Purified on protein A from tissue culture supernatant.

Format :

Purified IgG supplied in Phosphate buffered saline (PBS) containing 0.09% Sodium azide

Applications :

ELISA, Flow cyt, ICC/IF, IHC-Fr, IHC-P

Dilutions :

Optimal antibody dilution should be determined by titration

References :

Burchell J, et al. A short sequence, within the amino acid tandem repeat of a cancer-associated mucin, contains immunodominant epitopes. Int J Cancer.1989.44(4):691-6. PMID:2477336 http://www.ncbi.nlm.nih.gov/pubmed/2477336; Burchell J, et al. Development and characterization of breast cancer reactive monoclonal antibodies directed to the core protein of the human milk mucin. Cancer Res.1987. 47(20):5476-82. PMID:2443241 http://www.ncbi.nlm.nih.gov/pubmed/2443241

Database links :

Entrez Gene: 4582 Human; Omim: 158340 Human; SwissProt: P15941 Human; Unigene: 89603 Human

Research areas :

Epigenetics; DNA damage repair

Also known as :

Breast carcinoma-associated antigen DF3; Carcinoma-associated mucin; CD227; DF3 antigen; EMA; Episialin; H23 antigen; H23AG; KL-6; MAM6; MUC-1; MUC-1/SEC; MUC-1/X; MUC1; MUC1-alpha; MUC1-beta; MUC1-CT; MUC1-NT; MUC1/ZD; mucin 1, cell surface associated; mucin 1, transmembrane; Mucin-1; Mucin-1 subunit alpha; Mucin-1 subunit beta; Peanut-reactive urinary mucin; PEM; PEMT; Polymorphic epithelial mucin; PUM; tumor associated epithelial mucin; Tumor-associated epithelial membrane antigen; Tumor-associated mucin

Price (Pounds) :

226

Price (Dollars) :

345 USD

Price (Euros) :

338