Fbxw7/Cdc4 Antibody [FBOX 3a9/1]: Horseradish peroxidase (HRP)

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product summary

company name :

ImmuQuest

product type :

antibody

product name :

Fbxw7/Cdc4 Antibody [FBOX 3a9/1]: Horseradish peroxidase (HRP)

catalog :

IQ622HRP

quantity :

50 ul

clonality :

monoclonal

host :

mouse

conjugate :

HRP

clone name :

'FBOX 3a9/1

reactivity :

human, mouse

application :

western blot, immunoprecipitation, immunohistochemistry - paraffin section

product information

Product Name :

Fbxw7/Cdc4 Antibody [FBOX 3a9/1]: Horseradish peroxidase (HRP)

Target Antigen :

Fbxw7/Cdc4

Primary Description :

Mouse anti Fbxw7/Cdc4 [FBOX 3a9/1]: Horseradish peroxidase (HRP)

Catalogue Number :

IQ622HRP

Quantity :

50 ul

Concentration :

1mg/ml

Clone :

'FBOX 3a9/1

Host :

Mouse

Isotype :

IgG1

Immunogen :

Synthetic peptide of human sequence

Myeloma/fusion partners :

Cells from immunized mice were fused with the Sp2/0-Ag.14 myeloma cell line

Specificity :

This antibody recognises F-box/WD repeat-containing protein 7 (Fbxw7), which is also known as cdc4 and SEL-10. The FBW7/Cdc4 F-box protein was first recognized by its ability to bind cyclin E and the SCF (FBW7) is now known to target c-Myc, c-Jun and Notc

Species Reactivity :

Mouse, Human

Purification :

Purified on protein A from tissue culture supernatant.

Format :

Purified IgG conjugated to Horseradish Peroxidase using Innova Biosciences Lightning-LinkÂ®, supplied in Phosphate buffered saline (PBS) containing 0.01% Thiomersal

Applications :

IHC-P, IP, WB

Dilutions :

Optimal antibody dilution should be determined by titration

References :

Nateri AS, et al. The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling. Science. 2004.303(5662):1374-8. PMID:14739463 http://www.ncbi.nlm.nih.gov/pubmed/14739463

Database links :

Entrez Gene: 55294 Human; Entrez Gene: 50754 Mouse; Omim: 606278 Human; SwissProt: Q969H0 Human; SwissProt: Q0VGT7 Mouse; SwissProt: Q8VBV4 Mouse; Unigene: 519029 Human; Unigene: 196475 Mouse

Research areas :

Epigenetics; Ubiquitin conjugation pathway

Also known as :

AGO; Archipelago homolog; archipelago, Drosophila, homolog of; CDC4; DKFZp686F23254; F-box and WD repeat domain containing 7; F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila); F-box and WD-40 domain-containing protein 7; F-box protein FB

Price (Pounds) :

245

Price (Euros) :

366