HIF-1 alpha Antibody [ESEE122] | ImmuQuest IQ607 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

ImmuQuest

product type :

antibody

product name :

HIF-1 alpha Antibody [ESEE122]

catalog :

IQ607

quantity :

0.1 ml

price :

345 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

'ESEE122

reactivity :

human, mouse, rat, cow

application :

western blot, ELISA, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

product information

Product Name :

HIF-1 alpha Antibody [ESEE122]

Target Antigen :

HIF-1 alpha

Primary Description :

Mouse anti HIF-1 alpha [ESEE122]

Catalogue Number :

IQ607

Quantity :

0.1 ml

Concentration :

1mg/ml

Clone :

'ESEE122

Host :

Mouse

Isotype :

IgG1

Immunogen :

GST-human HIF-1A amino acids 329-530 fusion protein

Myeloma/fusion partners :

Cells from immunized Balb/c mice were fused with the NS1 myeloma cell line

Specificity :

This antibody recognises hypoxia-inducible factor 1 alpha (HIF-1 alpha). Induction of the Hif regulated genes, as a consequence of the microenvironment or genetic changes, is known to have an important role in the growth of experimental tumours. HIF1A has been observed in varying subsets of tumour cells from various solid tumours.

Species Reactivity :

Mouse, Rat, Cow, Human

Purification :

Purified on protein A from tissue culture supernatant.

Format :

Purified IgG supplied in Phosphate buffered saline (PBS) containing 0.09% Sodium azide

Applications :

ELISA, ICC/IF, IHC-Fr, IHC-P, WB

Dilutions :

Optimal antibody dilution should be determined by titration

References :

Talks KL, et al. The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages. Am J Pathol.2000.157(2):411-21. PMID:10934146 http://www.ncbi.nlm.nih.gov/pubmed/10934146

Database links :

Entrez Gene: 281814 Cow; Entrez Gene: 3091 Human; Entrez Gene: 15251 Mouse; Entrez Gene: 29560 Rat; Omim: 603348 Human; SwissProt: Q9XTA5 Cow; SwissProt: Q16665 Human; SwissProt: Q61221 Mouse; SwissProt: O35800 Rat; Unigene: 597216 Human; Unigene: 3879 Mouse; Unigene: 446610 Mouse; Unigene: 10852 Rat

Research areas :

Epigenetics; DNA binding; DNA damage repair; Transcription

Also known as :

ARNT interacting protein; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; BHLHE78; Class E basic helix-loop-helix protein 78; HIF-1-alpha; HIF-1alpha; HIF1; HIF1-alpha; HIF1A; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia-inducible factor 1 alpha isoform I.3; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); Hypoxia-inducible factor 1-alpha; Member of PAS protein 1; member of PAS superfamily 1; MOP1; PAS domain-containing protein 8; PASD8

Price (Pounds) :

226

Price (Dollars) :

345 USD

Price (Euros) :

338