Lamin B1 + B2 antibody [X223] - Nuclear Envelope Marker | ImmuQuest IQ176 product information

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product summary

company name :

ImmuQuest

product type :

antibody

product name :

Lamin B1 + B2 antibody [X223] - Nuclear Envelope Marker

catalog :

IQ176

quantity :

2 ml

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

'X223

reactivity :

human, mouse, rat, bovine

application :

western blot, immunocytochemistry

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; human	Bui K, von Appen A, DiGuilio A, Ori A, Sparks L, Mackmull M, et al. Integrated structural analysis of the human nuclear pore complex scaffold. Cell. 2013;155:1233-43 pubmed publisher
	Ulbert S, Antonin W, Platani M, Mattaj I. The inner nuclear membrane protein Lem2 is critical for normal nuclear envelope morphology. FEBS Lett. 2006;580:6435-41 pubmed

product information

Product Name :

Lamin B1 + B2 antibody [X223] - Nuclear Envelope Marker

Target Antigen :

Lamin B1 + B2 - Nuclear Envelope Marker

Primary Description :

Mouse Anti-Lamin B1 + B2 antibody [X223] - Nuclear Envelope Marker

Catalogue Number :

IQ176

Quantity :

2 ml

Concentration :

10-15ug/ml

Clone :

'X223

Host :

Mouse

Isotype :

IgG1

Immunogen :

Full length native lamin B2 protein (purified) (Xenopus laevis) (XLKE-A6 cells)

Specificity :

Reacts with COS cells in immunocytochemistry and is said to detect the karyoskeleton. Other cell/tissue types have not been tested. In mouse the antibody detects Lamin B2 only.

Species Reactivity :

Mouse, Rat, Cow, Human

Purification :

Unpurified

Format :

Tissue culture supernatant containing 0.09% sodium azide

Applications :

ICC/IF, WB

Dilutions :

Optimal antibody dilution should be determined by titration, however as a guideline try; ICC/IF: Use at an assay dependent dilution WB: 1/50. Predicted molecular weight: 65 - 67 kDa

References :

The nuclear lamins. A multigene family of proteins in evolution and differentiation. Krohne G ( Exp Cell Res.,Jan 1986) <a href="http://www.ncbi.nlm.nih.gov/pubmed/?term=he+nuclear+lamins.+A+multigene+family+of+proteins+in+evolution+and+differentiation" t

Database links :

Entrez Gene: 84823 Human Entrez

Research areas :

Apoptosis; Cell Biology; Class V Lamins; Cytoskeleton; Cytoskeleton / ECM; Intermediate Filaments; Lamins; Nuclear Envelope; Nucleus; Subcellular Markers; Tags Cell Markers;

Also known as :

Lamin B1 antibody;Lamin B2 antibody;LMN antibody;LMN B2 antibody;LMN2 antibody;LMNBantibody;LMNB1 antibody;LMNB2 antibody

Price (Pounds) :

226

Price (Euros) :

338