Anti Mucin-1 Glycoprotein Antibody | Hytest 4M40-M4H2 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Hytest

product type :

antibody

product name :

Anti Mucin-1 Glycoprotein Antibody

catalog :

4M40-M4H2

quantity :

1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

M4H2

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation, enzyme immunoassay

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; human western blot; human	Kovjazin R, Volovitz I, Kundel Y, Rosenbaum E, Medalia G, Horn G, et al. ImMucin: a novel therapeutic vaccine with promiscuous MHC binding for the treatment of MUC1-expressing tumors. Vaccine. 2011;29:4676-86 pubmed publisher
	Kovjazin R, Dubnik A, Horn G, Smorodinsky N, Hardan I, Shapira M, et al. Autoantibodies against the signal peptide domain of MUC1 in patients with multiple myeloma: Implications for disease diagnosis and prognosis. Exp Ther Med. 2012;3:1092-1098 pubmed

product information

Product Name :

Anti Mucin-1 Glycoprotein Antibody

Catalog Number :

4M40-M4H2

Spec:Description :

Specific for human MUC1 glycoprotein (peptide tandem repeat in MUC1 core). Affinity 1 x 108. Binds with high efficiency with different epitopes within the VNTR tandem repeat peptide region of MUC1 molecule, which have different conformations and peptide- carbohydrate compositions; reacts with VNTR20 recombinant unglycosylated fragment of MUC1 protein (and very weakly with monomeric MUC1 peptide), with deglycosylated and underglycosylated natural MUC1 (but not with completely glycosylated natural milk MUC1). Can be used for immunohistochemical staining of paraffin and frozen sections of breast, lung and ovarian tumor tissues. They may be used for staining of paraffin-embedded tissue sections fixed in neutral-buffered formalin and is compatible with commonly used histological fixatives. Also can be used in the form of enzyme conjugates for development in ELISA sandwich assays of under-glycosylated tumor-associated MUC1 mucins in human serum. They may be used in conjunction with MAbs M9E7, M8C9, M10G4 and M10H6 specific to unglycosylated VNTR region of MUC1 as capture reagents

Spec:Quantity :

1 mg

Categorization :

Antibodies

Spec:Clonality :

Monoclonal Antibody

Spec:Applications :

EIA, IHC

Spec:Host :

Mouse

Spec:Clone :

M4H2

Spec:Reactivity :

human

Spec:Conjugate/Tag/Label :

Unconjugated

Spec:Brand/Trademark :

HyTest Ltd

Spec:Isotype :

IgG

Spec:Target :

Anti Mucin-1 Glycoprotein Antibody