This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Hytest
product type :
antibody
product name :
Anti Insulin/Proinsulin, Rat-mouse Antibody
catalog :
2IP10-D6C4
quantity :
1 mg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
D6C4
reactivity :
human, mouse, rat
application :
immunohistochemistry, enzyme immunoassay, immunohistochemistry - paraffin section
citations: 5
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:200; fig s5
Li X, Cheng K, Liu Z, Yang J, Wang B, Jiang X, et al. The MDM2-p53-pyruvate carboxylase signalling axis couples mitochondrial metabolism to glucose-stimulated insulin secretion in pancreatic β-cells. Nat Commun. 2016;7:11740 pubmed publisher
  • ELISA; mouse; 1:1000; fig 8
Shinohara M, Kimura H, Montagne K, Komori K, Fujii T, Sakai Y. Combination of microwell structures and direct oxygenation enables efficient and size-regulated aggregate formation of an insulin-secreting pancreatic ?-cell line. Biotechnol Prog. 2014;30:178-87 pubmed publisher
Shu L, Zhong L, Xiao Y, Wu X, Liu Y, Jiang X, et al. Neutrophil elastase triggers the development of autoimmune diabetes by exacerbating innate immune responses in pancreatic islets of non-obese diabetic mice. Clin Sci (Lond). 2020;134:1679-1696 pubmed publisher
van Genderen F, Gorus F, Vermeulen I, Vekens E, De Pauw P, Pipeleers D, et al. Development of a multipurpose time-resolved fluorescence immunoassay for rat insulin. Anal Biochem. 2010;404:8-13 pubmed publisher
Belloul M, Engl W, Colin A, Panizza P, Ajdari A. Competition between local collisions and collective hydrodynamic feedback controls traffic flows in microfluidic networks. Phys Rev Lett. 2009;102:194502 pubmed
product information
Product Name :
Anti Insulin/Proinsulin, Rat-mouse Antibody
Catalog Number :
2IP10-D6C4
Spec:Description :
Specific for both rat and mouse insulin-proinsulin (different antigenic determinants), Kd 8.1 x 10-8 M. Cross-react with human, bovine and porcine insulin and proinsulin. Can be used: detection of rat-mouse insulin/proinsulin in two-site enzyme immunoassay, recommend pair (coating - conjugate): D6C4 - D3E7; for immunohistochemistry on frozen sections
Spec:Quantity :
1 mg
Categorization :
Antibodies
Spec:Clonality :
Monoclonal Antibody
Spec:Applications :
EIA, IHC
Spec:Host :
Mouse
Spec:Clone :
D6C4
Spec:Reactivity :
Rat, mouse, human, bovine and porcine insulin and proinsulin
Spec:Conjugate/Tag/Label :
Unconjugated
Spec:Brand/Trademark :
HyTest Ltd
Spec:Isotype :
IgG1
Spec:Target :
Anti Insulin/Proinsulin, Rat-mouse Antibody
company information
Hytest
Intelligate 6th floor
Joukahaisenkatu 6, 20520, Turku
hytest@hytest.fi
http://www.hytest.fi
358-2-512-0900
headquarters: Finland
HyTest Ltd. is a biotechnology-oriented company based in Turku, Finland, that manufactures and markets high-quality immunological reagents for industrial and research applications. The product portfolio includes cardiac markers, hormones and toxins, human proteins, neuroscience-related reagents, infectious and autoimmune disease reagents.