product summary
company name :
Hycult Biotech
product type :
antibody
product name :
MASP-2, Human, mAb 8B5
catalog :
HM2190-IA
quantity :
0.5 mg
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
8B5
reactivity :
human
application :
western blot, ELISA
more info or order :
citations: 7
Published Application/Species/Sample/DilutionReference
  • ELISA; human; loading ...; fig 2a
Sandahl T, Kelsen J, Dige A, Dahlerup J, Agnholt J, Hvas C, et al. The lectin pathway of the complement system is downregulated in Crohn's disease patients who respond to anti-TNF-? therapy. J Crohns Colitis. 2014;8:521-8 pubmed publisher
Henriksen M, Brandt J, Andrieu J, Nielsen C, Jensen P, Holmskov U, et al. Heteromeric complexes of native collectin kidney 1 and collectin liver 1 are found in the circulation with MASPs and activate the complement system. J Immunol. 2013;191:6117-27 pubmed publisher
Ma Y, Skjoedt M, Garred P. Collectin-11/MASP complex formation triggers activation of the lectin complement pathway--the fifth lectin pathway initiation complex. J Innate Immun. 2013;5:242-50 pubmed publisher
Csuka D, Munthe Fog L, Skjoedt M, Hein E, Bay J, Varga L, et al. A novel assay to quantitate MASP-2/ficolin-3 complexes in serum. J Immunol Methods. 2013;387:237-44 pubmed publisher
Pavlov V, Skjoedt M, Siow Tan Y, Rosbjerg A, Garred P, Stahl G. Endogenous and natural complement inhibitor attenuates myocardial injury and arterial thrombogenesis. Circulation. 2012;126:2227-35 pubmed publisher
Skjoedt M, Roversi P, Hummelshøj T, Palarasah Y, Rosbjerg A, Johnson S, et al. Crystal structure and functional characterization of the complement regulator mannose-binding lectin (MBL)/ficolin-associated protein-1 (MAP-1). J Biol Chem. 2012;287:32913-21 pubmed
Reichhardt M, Loimaranta V, Thiel S, Finne J, Meri S, Jarva H. The salivary scavenger and agglutinin binds MBL and regulates the lectin pathway of complement in solution and on surfaces. Front Immunol. 2012;3:205 pubmed publisher
product information
Catalog no :
HM2190-IA
Title :
MASP-2, Human, mAb 8B5
Clone no :
8B5
Quantity :
0.5 mg
Application code :
immunoassays,western blot
Species :
human
Host species :
rat
Isotype :
IgG1
Conjugate :
purified
Type :
mAb
Antigen :
MASP-2
Meta data :
CCP42-SP, MBL, serine protease, ficolin
more info or order :
company information
Hycult Biotech
Frontstraat 2a
5405 PB UDEN
support@hycultbiotech.com
www.hycultbiotech.com
31 0 413 25 13 35
headquarters: Netherlands
Hycult Biotech develops, produces and markets antibodies, antibody based products and more specifically immunoassays for innate immunity and directly related fields, with an emphasis on complement, neutrophil proteins, TLR, scavenger receptors and acute phase proteins. Furthermore, we have a strong interest in progressing research in the area of inflammation and cell damage caused by pathogens or oxidation factors.

Hycult Biotech’s mission and strategy is to advance insight in innate immunity related diseases, for the benefit of individuals and their quality of life.

As a leader within focused fields of immunology and cell biology, we develop products for the life sciences and in accordance with our mission it is our ambition to facilitate the transition of these products from research use into diagnostic testing. Many of our reagents are developed in close cooperation with scientists worldwide. Hycult Biotech has built a strong network with over 40 close scientific collaborations with leading international research institutes. We contribute to numerous projects and as a result, can continuously offer early access to an expanding range of innovative reagents. Hycult Biotech has been ISO-9001 certified since 1998 and we upgraded our certification to ISO-13485 in 2007, with a milestone of our first release of CE marked assays in 2009. Our vision, knowledgeable team and quality management system guarantee products of the highest grade combined with excellent technical service.