product summary
company name :
Hycult Biotech
product type :
antibody
product name :
EPCR, Human, mAb RCR-252, FITC
catalog :
HM2145F
quantity :
100 µg
clonality :
monoclonal
host :
rat
conjugate :
FITC
clone name :
RCR-252

The same clone is also sold as:
reactivity :
human
application :
western blot, immunoprecipitation, flow cytometry
more info or order :
Hycult Biotech product webpage
citations: 6
Reference
Yang J, Ikezoe T, Nishioka C, Honda G, Yokoyama A. Thrombomodulin-induced differentiation of acute myelomonocytic leukemia cells via JNK signaling. Leuk Res. 2012;36:625-33 pubmed publisher
Ikezoe T, Yang J, Nishioka C, Honda G, Furihata M, Yokoyama A. Thrombomodulin protects endothelial cells from a calcineurin inhibitor-induced cytotoxicity by upregulation of extracellular signal-regulated kinase/myeloid leukemia cell-1 signaling. Arterioscler Thromb Vasc Biol. 2012;32:2259-70 pubmed publisher
Mosnier L, Yang X, Griffin J. Activated protein C mutant with minimal anticoagulant activity, normal cytoprotective activity, and preservation of thrombin activable fibrinolysis inhibitor-dependent cytoprotective functions. J Biol Chem. 2007;282:33022-33 pubmed
Villegas-Mendez A, Montes R, Ambrose L, Warrens A, Laffan M, Lane D. Proteolysis of the endothelial cell protein C receptor by neutrophil proteinase 3. J Thromb Haemost. 2007;5:980-8 pubmed
Turner L, Lavstsen T, Berger S, Wang C, Petersen J, Avril M, et al. Severe malaria is associated with parasite binding to endothelial protein C receptor. Nature. 2013;498:502-5 pubmed publisher
Ikezoe T, Yang J, Nishioka C, Isaka M, Iwabu N, Sakai M, et al. Thrombomodulin enhances the antifibrinolytic and antileukemic effects of all-trans retinoic acid in acute promyelocytic leukemia cells. Exp Hematol. 2012;40:457-65 pubmed publisher
product information
Catalog no :
HM2145F
Title :
EPCR, Human, mAb RCR-252, FITC
Clone no :
RCR-252
Quantity :
100 µg
Application code :
flow cytometry,,functional studies,immunoprecipitation,western blot
Species :
human
Host species :
rat
Isotype :
IgG1
Conjugate :
FITC
Type :
mAb
Antigen :
EPCR
more info or order :
Hycult Biotech product webpage
company information
Hycult Biotech
Frontstraat 2a
5405 PB UDEN
support@hycultbiotech.com
www.hycultbiotech.com
31 0 413 25 13 35
headquarters: Netherlands
Hycult Biotech develops, produces and markets antibodies, antibody based products and more specifically immunoassays for innate immunity and directly related fields, with an emphasis on complement, neutrophil proteins, TLR, scavenger receptors and acute phase proteins. Furthermore, we have a strong interest in progressing research in the area of inflammation and cell damage caused by pathogens or oxidation factors.

Hycult Biotech’s mission and strategy is to advance insight in innate immunity related diseases, for the benefit of individuals and their quality of life.

As a leader within focused fields of immunology and cell biology, we develop products for the life sciences and in accordance with our mission it is our ambition to facilitate the transition of these products from research use into diagnostic testing. Many of our reagents are developed in close cooperation with scientists worldwide. Hycult Biotech has built a strong network with over 40 close scientific collaborations with leading international research institutes. We contribute to numerous projects and as a result, can continuously offer early access to an expanding range of innovative reagents. Hycult Biotech has been ISO-9001 certified since 1998 and we upgraded our certification to ISO-13485 in 2007, with a milestone of our first release of CE marked assays in 2009. Our vision, knowledgeable team and quality management system guarantee products of the highest grade combined with excellent technical service.