product summary
company name :
Hycult Biotech
product type :
antibody
product name :
CD46, Human, mAb M177
catalog :
HM2103
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
M177

The same clone is also sold as:
reactivity :
human
application :
western blot, immunoprecipitation, flow cytometry
more info or order :
Hycult Biotech product webpage
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:50; loading ...; fig 3a
Detsika M, Myrtsi E, Koulocheri S, Haroutounian S, Lianos E, Roussos C. Induction of decay accelerating factor and membrane cofactor protein by resveratrol attenuates complement deposition in human coronary artery endothelial cells. Biochem Biophys Rep. 2019;19:100652 pubmed publisher
Teigler J, Iampietro M, Barouch D. Vaccination with adenovirus serotypes 35, 26, and 48 elicits higher levels of innate cytokine responses than adenovirus serotype 5 in rhesus monkeys. J Virol. 2012;86:9590-8 pubmed publisher
Sugiyama T, Yoneda M, Kuraishi T, Hattori S, Inoue Y, Sato H, et al. Measles virus selectively blind to signaling lymphocyte activation molecule as a novel oncolytic virus for breast cancer treatment. Gene Ther. 2013;20:338-47 pubmed publisher
Johnson M, Petrovas C, Yamamoto T, Lindsay R, Loré K, Gall J, et al. Type I IFN induced by adenovirus serotypes 28 and 35 has multiple effects on T cell immunogenicity. J Immunol. 2012;188:6109-18 pubmed publisher
Adams W, Berenson R, Karlsson Hedestam G, Lieber A, Koup R, Lore K. Attenuation of CD4+ T-cell function by human adenovirus type 35 is mediated by the knob protein. J Gen Virol. 2012;93:1339-44 pubmed publisher
Matsui H, Sakurai F, Katayama K, Kurachi S, Tashiro K, Sugio K, et al. Enhanced transduction efficiency of fiber-substituted adenovirus vectors by the incorporation of RGD peptides in two distinct regions of the adenovirus serotype 35 fiber knob. Virus Res. 2011;155:48-54 pubmed publisher
Matsui H, Sakurai F, Kurachi S, Tashiro K, Sugio K, Kawabata K, et al. Development of fiber-substituted adenovirus vectors containing foreign peptides in the adenovirus serotype 35 fiber knob. Gene Ther. 2009;16:1050-7 pubmed publisher
Lore K, Adams W, Havenga M, Precopio M, Holterman L, Goudsmit J, et al. Myeloid and plasmacytoid dendritic cells are susceptible to recombinant adenovirus vectors and stimulate polyfunctional memory T cell responses. J Immunol. 2007;179:1721-9 pubmed
Fleischli C, Verhaagh S, Havenga M, Sirena D, Schaffner W, Cattaneo R, et al. The distal short consensus repeats 1 and 2 of the membrane cofactor protein CD46 and their distance from the cell membrane determine productive entry of species B adenovirus serotype 35. J Virol. 2005;79:10013-22 pubmed
product information
Catalog no :
HM2103
Title :
CD46, Human, mAb M177
Clone no :
M177
Quantity :
100 µg
Application code :
flow cytometry,functional studies,immunoassays,immunoprecipitation,western blot
Species :
Human
Host species :
mouse
Isotype :
IgG1
Conjugate :
purified
Aliases :
membrane cofactor protein, MCP
Type :
mAb
Antigen :
CD46
Meta data :
membrane cofactor protein, MCP
more info or order :
Hycult Biotech product webpage
company information
Hycult Biotech
Frontstraat 2a
5405 PB UDEN
support@hycultbiotech.com
http://www.hycultbiotech.com
31 0 413 25 13 35
headquarters: Netherlands
Hycult Biotech develops, produces and markets antibodies, antibody based products and more specifically immunoassays for innate immunity and directly related fields, with an emphasis on complement, neutrophil proteins, TLR, scavenger receptors and acute phase proteins. Furthermore, we have a strong interest in progressing research in the area of inflammation and cell damage caused by pathogens or oxidation factors.

Hycult Biotech’s mission and strategy is to advance insight in innate immunity related diseases, for the benefit of individuals and their quality of life.

As a leader within focused fields of immunology and cell biology, we develop products for the life sciences and in accordance with our mission it is our ambition to facilitate the transition of these products from research use into diagnostic testing. Many of our reagents are developed in close cooperation with scientists worldwide. Hycult Biotech has built a strong network with over 40 close scientific collaborations with leading international research institutes. We contribute to numerous projects and as a result, can continuously offer early access to an expanding range of innovative reagents. Hycult Biotech has been ISO-9001 certified since 1998 and we upgraded our certification to ISO-13485 in 2007, with a milestone of our first release of CE marked assays in 2009. Our vision, knowledgeable team and quality management system guarantee products of the highest grade combined with excellent technical service.