product summary
company name :
Hycult Biotech
product type :
antibody
product name :
C5aR, Human, mAb S5/1
catalog :
HM2094
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:50; loading ...; fig 3
Arias Cabrales C, Rodríguez García E, Gimeno J, Benito D, Pérez Sáez M, Redondo Pachón D, et al. Role of C5aR1 and C5L2 Receptors in Ischemia-Reperfusion Injury. J Clin Med. 2021;10: pubmed publisher
Croker D, Halai R, Fairlie D, Cooper M. C5a, but not C5a-des Arg, induces upregulation of heteromer formation between complement C5a receptors C5aR and C5L2. Immunol Cell Biol. 2013;91:625-33 pubmed publisher
van Werkhoven M, Damman J, van Dijk M, Daha M, de Jong I, Leliveld A, et al. Complement mediated renal inflammation induced by donor brain death: role of renal C5a-C5aR interaction. Am J Transplant. 2013;13:875-882 pubmed publisher
Li R, Coulthard L, Wu M, Taylor S, Woodruff T. C5L2: a controversial receptor of complement anaphylatoxin, C5a. FASEB J. 2013;27:855-64 pubmed publisher
van Werkhoven M, Damman J, Daha M, Krikke C, van Goor H, van Son W, et al. Novel insights in localization and expression levels of C5aR and C5L2 under native and post-transplant conditions in the kidney. Mol Immunol. 2013;53:237-45 pubmed publisher
Page T, D Souza Z, Nakanishi S, Serikawa T, Pusey C, Aitman T, et al. Role of novel rat-specific Fc receptor in macrophage activation associated with crescentic glomerulonephritis. J Biol Chem. 2012;287:5710-9 pubmed publisher
Raby A, Holst B, Davies J, Colmont C, Laumonnier Y, Coles B, et al. TLR activation enhances C5a-induced pro-inflammatory responses by negatively modulating the second C5a receptor, C5L2. Eur J Immunol. 2011;41:2741-52 pubmed publisher
Strey C, Siegmund B, Rosenblum S, Marquez Pinilla R, Oppermann E, Huber Lang M, et al. Complement and neutrophil function changes after liver resection in humans. World J Surg. 2009;33:2635-43 pubmed publisher
Gueler F, Rong S, Gwinner W, Mengel M, Bröcker V, Schön S, et al. Complement 5a receptor inhibition improves renal allograft survival. J Am Soc Nephrol. 2008;19:2302-12 pubmed publisher
product information
Catalog no :
HM2094
Title :
C5aR, Human, mAb S5/1
Clone no :
S5/1
Quantity :
100 µg
Application code :
flow cytometry,frozen sections,functional studies,paraffin sections,western blot
Species :
human
Host species :
mouse
Isotype :
IgG2a
Conjugate :
purified
Type :
mAb
Antigen :
C5aR
Meta data :
complement receptor
more info or order :
company information
Hycult Biotech
Frontstraat 2a
5405 PB UDEN
support@hycultbiotech.com
http://www.hycultbiotech.com
31 0 413 25 13 35
headquarters: Netherlands
Hycult Biotech develops, produces and markets antibodies, antibody based products and more specifically immunoassays for innate immunity and directly related fields, with an emphasis on complement, neutrophil proteins, TLR, scavenger receptors and acute phase proteins. Furthermore, we have a strong interest in progressing research in the area of inflammation and cell damage caused by pathogens or oxidation factors.

Hycult Biotech’s mission and strategy is to advance insight in innate immunity related diseases, for the benefit of individuals and their quality of life.

As a leader within focused fields of immunology and cell biology, we develop products for the life sciences and in accordance with our mission it is our ambition to facilitate the transition of these products from research use into diagnostic testing. Many of our reagents are developed in close cooperation with scientists worldwide. Hycult Biotech has built a strong network with over 40 close scientific collaborations with leading international research institutes. We contribute to numerous projects and as a result, can continuously offer early access to an expanding range of innovative reagents. Hycult Biotech has been ISO-9001 certified since 1998 and we upgraded our certification to ISO-13485 in 2007, with a milestone of our first release of CE marked assays in 2009. Our vision, knowledgeable team and quality management system guarantee products of the highest grade combined with excellent technical service.