product summary
company name :
Hycult Biotech
product type :
antibody
product name :
LL-37/CAP-18, Human, mAb 1-1C12
catalog :
HM2071
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1-1C12
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
Hycult Biotech product webpage
citations: 9
Published Application/Species/Sample/DilutionReference
  • ELISA; human
Boesch A, Zhao Y, Landman A, Garcia M, Fahey J, Wira C, et al. A multiplexed assay to detect antimicrobial peptides in biological fluids and cell secretions. J Immunol Methods. 2013;397:71-6 pubmed publisher
Schrumpf J, van Sterkenburg M, Verhoosel R, Zuyderduyn S, Hiemstra P. Interleukin 13 exposure enhances vitamin D-mediated expression of the human cathelicidin antimicrobial peptide 18/LL-37 in bronchial epithelial cells. Infect Immun. 2012;80:4485-94 pubmed publisher
Hertting O, Holm A, Lüthje P, Brauner H, Dyrdak R, Jonasson A, et al. Vitamin D induction of the human antimicrobial Peptide cathelicidin in the urinary bladder. PLoS ONE. 2010;5:e15580 pubmed publisher
Dick E, Prince L, Sabroe I. Ex vivo-expanded bone marrow CD34+ derived neutrophils have limited bactericidal ability. Stem Cells. 2008;26:2552-63 pubmed publisher
Bucki R, Namiot D, Namiot Z, Savage P, Janmey P. Salivary mucins inhibit antibacterial activity of the cathelicidin-derived LL-37 peptide but not the cationic steroid CSA-13. J Antimicrob Chemother. 2008;62:329-35 pubmed publisher
von Köckritz Blickwede M, Goldmann O, Thulin P, Heinemann K, Norrby Teglund A, Rohde M, et al. Phagocytosis-independent antimicrobial activity of mast cells by means of extracellular trap formation. Blood. 2008;111:3070-80 pubmed publisher
Coffelt S, Waterman R, Florez L, Honer zu Bentrup K, Zwezdaryk K, Tomchuck S, et al. Ovarian cancers overexpress the antimicrobial protein hCAP-18 and its derivative LL-37 increases ovarian cancer cell proliferation and invasion. Int J Cancer. 2008;122:1030-9 pubmed
Bucki R, Byfield F, Janmey P. Release of the antimicrobial peptide LL-37 from DNA/F-actin bundles in cystic fibrosis sputum. Eur Respir J. 2007;29:624-32 pubmed
Felgentreff K, Beisswenger C, Griese M, Gulder T, Bringmann G, Bals R. The antimicrobial peptide cathelicidin interacts with airway mucus. Peptides. 2006;27:3100-6 pubmed
product information
Catalog no :
HM2071
Title :
LL-37/CAP-18, Human, mAb 1-1C12
Clone no :
1-1C12
Quantity :
100 µg
Application code :
immunoassays,paraffin sections,western blot,immunofluorescence
Species :
human
Host species :
mouse
Isotype :
IgG1
Conjugate :
purified
Aliases :
CAP18
Type :
mAb
Antigen :
LL-37
Meta data :
Cathelicidins, FPRL1, P2X8, CAP18
more info or order :
Hycult Biotech product webpage
company information
Hycult Biotech
Frontstraat 2a
5405 PB UDEN
support@hycultbiotech.com
www.hycultbiotech.com
31 0 413 25 13 35
headquarters: Netherlands
Hycult Biotech develops, produces and markets antibodies, antibody based products and more specifically immunoassays for innate immunity and directly related fields, with an emphasis on complement, neutrophil proteins, TLR, scavenger receptors and acute phase proteins. Furthermore, we have a strong interest in progressing research in the area of inflammation and cell damage caused by pathogens or oxidation factors.

Hycult Biotech’s mission and strategy is to advance insight in innate immunity related diseases, for the benefit of individuals and their quality of life.

As a leader within focused fields of immunology and cell biology, we develop products for the life sciences and in accordance with our mission it is our ambition to facilitate the transition of these products from research use into diagnostic testing. Many of our reagents are developed in close cooperation with scientists worldwide. Hycult Biotech has built a strong network with over 40 close scientific collaborations with leading international research institutes. We contribute to numerous projects and as a result, can continuously offer early access to an expanding range of innovative reagents. Hycult Biotech has been ISO-9001 certified since 1998 and we upgraded our certification to ISO-13485 in 2007, with a milestone of our first release of CE marked assays in 2009. Our vision, knowledgeable team and quality management system guarantee products of the highest grade combined with excellent technical service.