product summary
company name :
Hycult Biotech
product type :
antibody
product name :
HNP1-3, Human, mAb D21
catalog :
HM2058
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
D21
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
Hycult Biotech product webpage
citations: 12
Published Application/Species/Sample/DilutionReference
  • ELISA; human
Boesch A, Zhao Y, Landman A, Garcia M, Fahey J, Wira C, et al. A multiplexed assay to detect antimicrobial peptides in biological fluids and cell secretions. J Immunol Methods. 2013;397:71-6 pubmed publisher
Droin N, Jacquel A, Hendra J, Racoeur C, Truntzer C, Pecqueur D, et al. Alpha-defensins secreted by dysplastic granulocytes inhibit the differentiation of monocytes in chronic myelomonocytic leukemia. Blood. 2010;115:78-88 pubmed publisher
Adisen E, Yuksek J, Erdem O, Aksakal F, Aksakal A. Expression of human neutrophil proteins in acne vulgaris. J Eur Acad Dermatol Venereol. 2010;24:32-7 pubmed publisher
Morel E, Alvarez L, Cabanas R, Fiandor A, Diaz R, Escamochero S, et al. Expression of α-defensin 1-3 in T cells from severe cutaneous drug-induced hypersensitivity reactions. Allergy. 2011;66:360-7 pubmed publisher
Rodríguez-García M, Oliva H, Climent N, Garcia F, Gatell J, Gallart T. Human immature monocyte-derived dendritic cells produce and secrete alpha-defensins 1-3. J Leukoc Biol. 2007;82:1143-6 pubmed
Neuwirth A, Dobes J, Oujezdská J, Ballek O, Benesova M, Sumnik Z, et al. Eosinophils from patients with type 1 diabetes mellitus express high level of myeloid alpha-defensins and myeloperoxidase. Cell Immunol. 2012;273:158-63 pubmed publisher
Rensen S, Slaats Y, Nijhuis J, Jans A, Bieghs V, Driessen A, et al. Increased hepatic myeloperoxidase activity in obese subjects with nonalcoholic steatohepatitis. Am J Pathol. 2009;175:1473-82 pubmed publisher
Schenk M, Bouchon A, Birrer S, Colonna M, Mueller C. Macrophages expressing triggering receptor expressed on myeloid cells-1 are underrepresented in the human intestine. J Immunol. 2005;174:517-24 pubmed
Rodríguez-García M, Climent N, Oliva H, Casanova V, Franco R, Leon A, et al. Increased alpha-defensins 1-3 production by dendritic cells in HIV-infected individuals is associated with slower disease progression. PLoS ONE. 2010;5:e9436 pubmed publisher
Gow J, Hagan S, Herzyk P, Cannon C, Behan P, Chaudhuri A. A gene signature for post-infectious chronic fatigue syndrome. BMC Med Genomics. 2009;2:38 pubmed publisher
D'Agostino C, Lichtner M, Mastroianni C, Ceccarelli G, Iannetta M, Antonucci S, et al. In vivo release of alpha-defensins in plasma, neutrophils and CD8 T-lymphocytes of patients with HIV infection. Curr HIV Res. 2009;7:650-5 pubmed
Driss V, Legrand F, Hermann E, Loiseau S, Guerardel Y, Kremer L, et al. TLR2-dependent eosinophil interactions with mycobacteria: role of alpha-defensins. Blood. 2009;113:3235-44 pubmed publisher
product information
Catalog no :
HM2058
Title :
HNP1-3, Human, mAb D21
Clone no :
D21
Quantity :
100 µg
Application code :
frozen sections,flow cytometry,functional studies,immunoprecipitation,immunofluorescence,immunoassays,western blot,paraffin sections
Species :
human
Cross reactivity :
monkey
Host species :
mouse
Isotype :
IgG1
Conjugate :
purified
Aliases :
alpha-defensins 1-3
Type :
mAb
Antigen :
HNP1-3
Meta data :
alpha-defensins 1-3, HIV
more info or order :
Hycult Biotech product webpage
company information
Hycult Biotech
Frontstraat 2a
5405 PB UDEN
support@hycultbiotech.com
www.hycultbiotech.com
31 0 413 25 13 35
headquarters: Netherlands
Hycult Biotech develops, produces and markets antibodies, antibody based products and more specifically immunoassays for innate immunity and directly related fields, with an emphasis on complement, neutrophil proteins, TLR, scavenger receptors and acute phase proteins. Furthermore, we have a strong interest in progressing research in the area of inflammation and cell damage caused by pathogens or oxidation factors.

Hycult Biotech’s mission and strategy is to advance insight in innate immunity related diseases, for the benefit of individuals and their quality of life.

As a leader within focused fields of immunology and cell biology, we develop products for the life sciences and in accordance with our mission it is our ambition to facilitate the transition of these products from research use into diagnostic testing. Many of our reagents are developed in close cooperation with scientists worldwide. Hycult Biotech has built a strong network with over 40 close scientific collaborations with leading international research institutes. We contribute to numerous projects and as a result, can continuously offer early access to an expanding range of innovative reagents. Hycult Biotech has been ISO-9001 certified since 1998 and we upgraded our certification to ISO-13485 in 2007, with a milestone of our first release of CE marked assays in 2009. Our vision, knowledgeable team and quality management system guarantee products of the highest grade combined with excellent technical service.