product summary
company name :
Hycult Biotech
product type :
antibody
product name :
TNF-R II, Human, mAb MR2-1
catalog :
HM2007-FS
quantity :
0.5 mg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MR2-1

The same clone is also sold as:
reactivity :
human
application :
western blot, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 3
Reference
Gerspach J, Muller D, Munkel S, Selchow O, Nemeth J, Noack M, et al. Restoration of membrane TNF-like activity by cell surface targeting and matrix metalloproteinase-mediated processing of a TNF prodrug. Cell Death Differ. 2006;13:273-84 pubmed
Richter C, Messerschmidt S, Holeiter G, Tepperink J, Osswald S, Zappe A, et al. The tumor necrosis factor receptor stalk regions define responsiveness to soluble versus membrane-bound ligand. Mol Cell Biol. 2012;32:2515-29 pubmed publisher
Lisby S, Faurschou A, Gniadecki R. The autocrine TNFalpha signalling loop in keratinocytes requires atypical PKC species and NF-kappaB activation but is independent of cholesterol-enriched membrane microdomains. Biochem Pharmacol. 2007;73:526-33 pubmed
product information
Catalog no :
HM2007-FS
Title :
TNF-R II, Human, mAb MR2-1
Clone no :
MR2-1
Quantity :
0.5 mg
Application code :
functional studies,flow cytometry,frozen sections,western blot,,immunoprecipitation,immunoassays
Species :
human
Cross reactivity :
cynomolgus monkey, rhesus monkey
Host species :
mouse
Isotype :
IgG1
Conjugate :
purified
Aliases :
p75/p80, TNF-R2, CD120b
Type :
mAb
Antigen :
TNF-R II
Meta data :
p75/p80, TNF-R2, CD120b
more info or order :
company information
Hycult Biotech
Frontstraat 2a
5405 PB UDEN
support@hycultbiotech.com
www.hycultbiotech.com
31 0 413 25 13 35
headquarters: Netherlands
Hycult Biotech develops, produces and markets antibodies, antibody based products and more specifically immunoassays for innate immunity and directly related fields, with an emphasis on complement, neutrophil proteins, TLR, scavenger receptors and acute phase proteins. Furthermore, we have a strong interest in progressing research in the area of inflammation and cell damage caused by pathogens or oxidation factors.

Hycult Biotech’s mission and strategy is to advance insight in innate immunity related diseases, for the benefit of individuals and their quality of life.

As a leader within focused fields of immunology and cell biology, we develop products for the life sciences and in accordance with our mission it is our ambition to facilitate the transition of these products from research use into diagnostic testing. Many of our reagents are developed in close cooperation with scientists worldwide. Hycult Biotech has built a strong network with over 40 close scientific collaborations with leading international research institutes. We contribute to numerous projects and as a result, can continuously offer early access to an expanding range of innovative reagents. Hycult Biotech has been ISO-9001 certified since 1998 and we upgraded our certification to ISO-13485 in 2007, with a milestone of our first release of CE marked assays in 2009. Our vision, knowledgeable team and quality management system guarantee products of the highest grade combined with excellent technical service.