product summary
company name :
Hycult Biotech
product type :
antibody
product name :
Dectin-1, Mouse, mAb 2A11
catalog :
HM1067
quantity :
100 µg
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
2A11
reactivity :
mouse
application :
immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
more info or order :
Hycult Biotech product webpage
citations: 11
Reference
Li X, Wang J, Wang W, Liu C, Sun S, Gu J, et al. Immunomodulatory activity of a novel, synthetic beta-glucan (?-glu6) in murine macrophages and human peripheral blood mononuclear cells. PLoS ONE. 2013;8:e80399 pubmed publisher
Halloran S, Launoy G, Zappa M. European guidelines for quality assurance in colorectal cancer screening and diagnosis. First Edition--Faecal occult blood testing. Endoscopy. 2012;44 Suppl 3:SE65-87 pubmed
Yamanaka D, Motoi M, Ishibashi K, Miura N, Adachi Y, Ohno N. Effect of Agaricus brasiliensis-derived cold water extract on Toll-like receptor 2-dependent cytokine production in vitro. Immunopharmacol Immunotoxicol. 2012;34:561-70 pubmed publisher
Masuda Y, Togo T, Mizuno S, Konishi M, Nanba H. Soluble ?-glucan from Grifola frondosa induces proliferation and Dectin-1/Syk signaling in resident macrophages via the GM-CSF autocrine pathway. J Leukoc Biol. 2012;91:547-56 pubmed publisher
Tada R, Yoshikawa M, Ikeda F, Adachi Y, Kato Y, Kuge T, et al. Induction of IFN-? by a highly branched 1,3-?-d-glucan from Aureobasidium pullulans in mouse-derived splenocytes via dectin-1-independent pathways. Biochem Biophys Res Commun. 2011;404:1105-10 pubmed publisher
Nakamura M, Watanabe N. Ubiquitin-like protein MNSF?/endophilin II complex regulates Dectin-1-mediated phagocytosis and inflammatory responses in macrophages. Biochem Biophys Res Commun. 2010;401:257-61 pubmed publisher
Burton O, Zaccone P, Phillips J, De la Peña H, Fehervari Z, Azuma M, et al. Roles for TGF-beta and programmed cell death 1 ligand 1 in regulatory T cell expansion and diabetes suppression by zymosan in nonobese diabetic mice. J Immunol. 2010;185:2754-62 pubmed publisher
Masuda Y, Ito K, Konishi M, Nanba H. A polysaccharide extracted from Grifola frondosa enhances the anti-tumor activity of bone marrow-derived dendritic cell-based immunotherapy against murine colon cancer. Cancer Immunol Immunother. 2010;59:1531-41 pubmed publisher
Luther K, Torosantucci A, Brakhage A, Heesemann J, Ebel F. Phagocytosis of Aspergillus fumigatus conidia by murine macrophages involves recognition by the dectin-1 beta-glucan receptor and Toll-like receptor 2. Cell Microbiol. 2007;9:368-81 pubmed
Dupasquier M, Stoitzner P, Wan H, Cerqueira D, van Oudenaren A, Voerman J, et al. The dermal microenvironment induces the expression of the alternative activation marker CD301/mMGL in mononuclear phagocytes, independent of IL-4/IL-13 signaling. J Leukoc Biol. 2006;80:838-49 pubmed
Biswas S, Gangi L, Paul S, Schioppa T, Saccani A, Sironi M, et al. A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation). Blood. 2006;107:2112-22 pubmed
product information
Catalog no :
HM1067
Title :
Dectin-1, Mouse, mAb 2A11
Clone no :
2A11
Quantity :
100 µg
Application code :
frozen sections,flow cytometry,functional studies,immunoprecipitation
Species :
mouse
Host species :
rat
Isotype :
IgG2b
Conjugate :
purified
Aliases :
Beta-Glucan Receptor, Dectin-1, CLEC7A, DC-associated C-type lectin 1
Type :
mAb
Antigen :
Dectin-1
Meta data :
Beta-Glucan Receptor, Dectin-1, CLEC7A, DC-associated C-type lectin 1
more info or order :
Hycult Biotech product webpage
company information
Hycult Biotech
Frontstraat 2a
5405 PB UDEN
support@hycultbiotech.com
www.hycultbiotech.com
31 0 413 25 13 35
headquarters: Netherlands
Hycult Biotech develops, produces and markets antibodies, antibody based products and more specifically immunoassays for innate immunity and directly related fields, with an emphasis on complement, neutrophil proteins, TLR, scavenger receptors and acute phase proteins. Furthermore, we have a strong interest in progressing research in the area of inflammation and cell damage caused by pathogens or oxidation factors.

Hycult Biotech’s mission and strategy is to advance insight in innate immunity related diseases, for the benefit of individuals and their quality of life.

As a leader within focused fields of immunology and cell biology, we develop products for the life sciences and in accordance with our mission it is our ambition to facilitate the transition of these products from research use into diagnostic testing. Many of our reagents are developed in close cooperation with scientists worldwide. Hycult Biotech has built a strong network with over 40 close scientific collaborations with leading international research institutes. We contribute to numerous projects and as a result, can continuously offer early access to an expanding range of innovative reagents. Hycult Biotech has been ISO-9001 certified since 1998 and we upgraded our certification to ISO-13485 in 2007, with a milestone of our first release of CE marked assays in 2009. Our vision, knowledgeable team and quality management system guarantee products of the highest grade combined with excellent technical service.