product summary
company name :
Hycult Biotech
product type :
antibody
product name :
TLR9, Mouse, mAb 5G5, biotinylated
catalog :
HM1043
quantity :
50 µg
clonality :
monoclonal
host :
mouse
conjugate :
biotin
clone name :
5G5

The same clone is also sold as:
reactivity :
human, mouse, dog
application :
western blot, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
Hycult Biotech product webpage
citations: 16
Reference
Chaturvedi A, Dorward D, Pierce S. The B cell receptor governs the subcellular location of Toll-like receptor 9 leading to hyperresponses to DNA-containing antigens. Immunity. 2008;28:799-809 pubmed publisher
Selleri S, Arnaboldi F, Palazzo M, Gariboldi S, Zanobbio L, Opizzi E, et al. Toll-like receptor agonists regulate beta-defensin 2 release in hair follicle. Br J Dermatol. 2007;156:1172-7 pubmed
Fiola S, Gosselin D, Takada K, Gosselin J. TLR9 contributes to the recognition of EBV by primary monocytes and plasmacytoid dendritic cells. J Immunol. 2010;185:3620-31 pubmed publisher
Burgener I, Jungi T. Antibodies specific for human or murine Toll-like receptors detect canine leukocytes by flow cytometry. Vet Immunol Immunopathol. 2008;124:184-91 pubmed publisher
Wei X, Li Y, Sun X, Zhu X, Feng Y, Liu J, et al. Erythropoietin protects against murine cerebral malaria through actions on host cellular immunity. Infect Immun. 2014;82:165-73 pubmed publisher
Chen L, Arora M, Yarlagadda M, Oriss T, Krishnamoorthy N, Ray A, et al. Distinct responses of lung and spleen dendritic cells to the TLR9 agonist CpG oligodeoxynucleotide. J Immunol. 2006;177:2373-83 pubmed
Methe H, Kim J, Kofler S, Weis M, Nabauer M, Koglin J. Expansion of circulating Toll-like receptor 4-positive monocytes in patients with acute coronary syndrome. Circulation. 2005;111:2654-61 pubmed
Zhu X, Pan Y, Li Y, Jiang Y, Shang H, Gowda D, et al. Targeting Toll-like receptors by chloroquine protects mice from experimental cerebral malaria. Int Immunopharmacol. 2012;13:392-7 pubmed publisher
Azulay-Debby H, Edry E, Melamed D. CpG DNA stimulates autoreactive immature B cells in the bone marrow. Eur J Immunol. 2007;37:1463-75 pubmed
Tsujimoto H, Ono S, Matsumoto A, Kawabata T, Kinoshita M, Majima T, et al. A critical role of CpG motifs in a murine peritonitis model by their binding to highly expressed toll-like receptor-9 on liver NKT cells. J Hepatol. 2006;45:836-43 pubmed
Wang M, Cao Y, Luo E, Zhang Y, Guo Y. Pre-existing Schistosoma japonicum infection alters the immune response to Plasmodium berghei infection in C57BL/6 mice. Malar J. 2013;12:322 pubmed publisher
de Mast Q, de Groot P, van Heerde W, Roestenberg M, van Velzen J, Verbruggen B, et al. Thrombocytopenia in early malaria is associated with GP1b shedding in absence of systemic platelet activation and consumptive coagulopathy. Br J Haematol. 2010;151:495-503 pubmed publisher
Tokumasa N, Suto A, Kagami S, Furuta S, Hirose K, Watanabe N, et al. Expression of Tyk2 in dendritic cells is required for IL-12, IL-23, and IFN-gamma production and the induction of Th1 cell differentiation. Blood. 2007;110:553-60 pubmed
Xu W, He B, Chiu A, Chadburn A, Shan M, Buldys M, et al. Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI. Nat Immunol. 2007;8:294-303 pubmed
Pompei L, Jang S, Zamlynny B, Ravikumar S, McBride A, Hickman S, et al. Disparity in IL-12 release in dendritic cells and macrophages in response to Mycobacterium tuberculosis is due to use of distinct TLRs. J Immunol. 2007;178:5192-9 pubmed
Abe M, Thomson A. Dexamethasone preferentially suppresses plasmacytoid dendritic cell differentiation and enhances their apoptotic death. Clin Immunol. 2006;118:300-6 pubmed
product information
Catalog no :
HM1043
Title :
TLR9, Mouse, mAb 5G5, biotinylated
Clone no :
5G5
Quantity :
50 µg
Application code :
flow cytometry,western blot,immunoassays,frozen sections,paraffin sections
Species :
mouse
Cross reactivity :
canine, human
Host species :
mouse
Isotype :
IgG2a
Conjugate :
biotinylated
Aliases :
TRL9, CD289
Type :
mAb
Antigen :
TLR9, CD289
Meta data :
Toll-like receptor 9, CD289
more info or order :
Hycult Biotech product webpage
company information
Hycult Biotech
Frontstraat 2a
5405 PB UDEN
support@hycultbiotech.com
www.hycultbiotech.com
31 0 413 25 13 35
headquarters: Netherlands
Hycult Biotech develops, produces and markets antibodies, antibody based products and more specifically immunoassays for innate immunity and directly related fields, with an emphasis on complement, neutrophil proteins, TLR, scavenger receptors and acute phase proteins. Furthermore, we have a strong interest in progressing research in the area of inflammation and cell damage caused by pathogens or oxidation factors.

Hycult Biotech’s mission and strategy is to advance insight in innate immunity related diseases, for the benefit of individuals and their quality of life.

As a leader within focused fields of immunology and cell biology, we develop products for the life sciences and in accordance with our mission it is our ambition to facilitate the transition of these products from research use into diagnostic testing. Many of our reagents are developed in close cooperation with scientists worldwide. Hycult Biotech has built a strong network with over 40 close scientific collaborations with leading international research institutes. We contribute to numerous projects and as a result, can continuously offer early access to an expanding range of innovative reagents. Hycult Biotech has been ISO-9001 certified since 1998 and we upgraded our certification to ISO-13485 in 2007, with a milestone of our first release of CE marked assays in 2009. Our vision, knowledgeable team and quality management system guarantee products of the highest grade combined with excellent technical service.