product summary
company name :
Hycult Biotech
product type :
antibody
product name :
MBL-A, Mouse, mAb 8G6
catalog :
HM1035
quantity :
100 µg
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
8G6
reactivity :
mouse
application :
western blot, immunocytochemistry, immunohistochemistry - frozen section
more info or order :
Hycult Biotech product webpage
citations: 9
Reference
Held K, Thiel S, Loos M, Petry F. Increased susceptibility of complement factor B/C2 double knockout mice and mannan-binding lectin knockout mice to systemic infection with Candida albicans. Mol Immunol. 2008;45:3934-41 pubmed publisher
Windbichler M, Echtenacher B, Takahashi K, Ezekowitz R, Schwaeble W, Jenseniuis J, et al. Investigations on the involvement of the lectin pathway of complement activation in anaphylaxis. Int Arch Allergy Immunol. 2006;141:11-23 pubmed
Hirano M, Ma B, Kawasaki N, Oka S, Kawasaki T. Role of interaction of mannan-binding protein with meprins at the initial step of complement activation in ischemia/reperfusion injury to mouse kidney. Glycobiology. 2012;22:84-95 pubmed publisher
Pumidonming W, Walochnik J, Dauber E, Petry F. Binding to complement factors and activation of the alternative pathway by Acanthamoeba. Immunobiology. 2011;216:225-33 pubmed publisher
Endo Y, Iwaki D, Ishida Y, Takahashi M, Matsushita M, Fujita T. Mouse ficolin B has an ability to form complexes with mannose-binding lectin-associated serine proteases and activate complement through the lectin pathway. J Biomed Biotechnol. 2012;2012:105891 pubmed publisher
Abe Y, Kuroda Y, Kuboki N, Matsushita M, Yokoyama N, Kojima N. Contribution of complement component C3 and complement receptor type 3 to carbohydrate-dependent uptake of oligomannose-coated liposomes by peritoneal macrophages. J Biochem. 2008;144:563-70 pubmed publisher
Matthijsen R, de Winther M, Kuipers D, van der Made I, Weber C, Herias M, et al. Macrophage-specific expression of mannose-binding lectin controls atherosclerosis in low-density lipoprotein receptor-deficient mice. Circulation. 2009;119:2188-95 pubmed publisher
Petry F, Jakobi V, Wagner S, Tessema T, Thiel S, Loos M. Binding and activation of human and mouse complement by Cryptosporidium parvum (Apicomplexa) and susceptibility of C1q- and MBL-deficient mice to infection. Mol Immunol. 2008;45:3392-400 pubmed publisher
Chaouat G, Petitbarat M, Bulla R, Dubanchet S, Valdivia K, Ledee N, et al. Early regulators in abortion and implications for a preeclampsia model. J Reprod Immunol. 2009;82:131-40 pubmed publisher
product information
Catalog no :
HM1035
Title :
MBL-A, Mouse, mAb 8G6
Clone no :
8G6
Quantity :
100 µg
Application code :
frozen sections,immunoassays,immunofluorescence,western blot
Species :
mouse
Host species :
rat
Isotype :
IgG
Conjugate :
purified
Aliases :
MBL-A
Type :
mAb
Antigen :
MBL-A
Meta data :
MBL-A, MBP, C4, C3, C2, C1s
more info or order :
Hycult Biotech product webpage
company information
Hycult Biotech
Frontstraat 2a
5405 PB UDEN
support@hycultbiotech.com
www.hycultbiotech.com
31 0 413 25 13 35
headquarters: Netherlands
Hycult Biotech develops, produces and markets antibodies, antibody based products and more specifically immunoassays for innate immunity and directly related fields, with an emphasis on complement, neutrophil proteins, TLR, scavenger receptors and acute phase proteins. Furthermore, we have a strong interest in progressing research in the area of inflammation and cell damage caused by pathogens or oxidation factors.

Hycult Biotech’s mission and strategy is to advance insight in innate immunity related diseases, for the benefit of individuals and their quality of life.

As a leader within focused fields of immunology and cell biology, we develop products for the life sciences and in accordance with our mission it is our ambition to facilitate the transition of these products from research use into diagnostic testing. Many of our reagents are developed in close cooperation with scientists worldwide. Hycult Biotech has built a strong network with over 40 close scientific collaborations with leading international research institutes. We contribute to numerous projects and as a result, can continuously offer early access to an expanding range of innovative reagents. Hycult Biotech has been ISO-9001 certified since 1998 and we upgraded our certification to ISO-13485 in 2007, with a milestone of our first release of CE marked assays in 2009. Our vision, knowledgeable team and quality management system guarantee products of the highest grade combined with excellent technical service.