product summary
company name :
Hycult Biotech
product type :
antibody
product name :
TLR4/MD-2, Mouse, mAb MTS510
catalog :
HM1029-FS
quantity :
0.5 mg
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
MTS510
reactivity :
mouse
application :
immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 11
Reference
Jozefowski S, Biedroń R, Sróttek M, Chadzinska M, Marcinkiewicz J. The class A scavenger receptor SR-A/CD204 and the class B scavenger receptor CD36 regulate immune functions of macrophages differently. Innate Immun. 2014;20:826-47 pubmed publisher
Yamanaka D, Motoi M, Ishibashi K, Miura N, Adachi Y, Ohno N. Effect of Agaricus brasiliensis-derived cold water extract on Toll-like receptor 2-dependent cytokine production in vitro. Immunopharmacol Immunotoxicol. 2012;34:561-70 pubmed publisher
He M, Ichinose T, Yoshida S, Yamamoto S, Inoue K, Takano H, et al. Asian sand dust enhances murine lung inflammation caused by Klebsiella pneumoniae. Toxicol Appl Pharmacol. 2012;258:237-47 pubmed publisher
Lee J, Hong E. Immunostimulating activity of the polysaccharides isolated from Cordyceps militaris. Int Immunopharmacol. 2011;11:1226-33 pubmed publisher
Sánchez D, Rojas M, Hernandez I, Radzioch D, Garcia L, Barrera L. Role of TLR2- and TLR4-mediated signaling in Mycobacterium tuberculosis-induced macrophage death. Cell Immunol. 2010;260:128-36 pubmed publisher
Gross P, Brandl K, Dierkes C, Scholmerich J, Salzberger B, Gluck T, et al. Lipopolysaccharide-trap-Fc, a multifunctional agent to battle gram-negative bacteria. Infect Immun. 2009;77:2925-31 pubmed publisher
Burgener I, Jungi T. Antibodies specific for human or murine Toll-like receptors detect canine leukocytes by flow cytometry. Vet Immunol Immunopathol. 2008;124:184-91 pubmed publisher
Satta N, Dunoyer Geindre S, Reber G, Fish R, Boehlen F, Kruithof E, et al. The role of TLR2 in the inflammatory activation of mouse fibroblasts by human antiphospholipid antibodies. Blood. 2007;109:1507-14 pubmed
Tsujimoto H, Ono S, Matsumoto A, Kawabata T, Kinoshita M, Majima T, et al. A critical role of CpG motifs in a murine peritonitis model by their binding to highly expressed toll-like receptor-9 on liver NKT cells. J Hepatol. 2006;45:836-43 pubmed
Chen L, Arora M, Yarlagadda M, Oriss T, Krishnamoorthy N, Ray A, et al. Distinct responses of lung and spleen dendritic cells to the TLR9 agonist CpG oligodeoxynucleotide. J Immunol. 2006;177:2373-83 pubmed
Akashi S, Saitoh S, Wakabayashi Y, Kikuchi T, Takamura N, Nagai Y, et al. Lipopolysaccharide interaction with cell surface Toll-like receptor 4-MD-2: higher affinity than that with MD-2 or CD14. J Exp Med. 2003;198:1035-42 pubmed
product information
Catalog no :
HM1029-FS
Title :
TLR4/MD-2, Mouse, mAb MTS510
Clone no :
MTS510
Quantity :
0.5 mg
Application code :
frozen sections,flow cytometry,functional studies,immunoprecipitation
Species :
mouse
Host species :
rat
Isotype :
IgG2a
Conjugate :
purified
Aliases :
TRL4, CD284, lymfocyte antigen 96, ESOP-1
Type :
mAb
Antigen :
TLR4/MD-2, CD284/MD-2
Meta data :
Toll-like receptor 4, CD284, lymfocyte antigen 96, ESOP-1
more info or order :
company information
Hycult Biotech
Frontstraat 2a
5405 PB UDEN
support@hycultbiotech.com
www.hycultbiotech.com
31 0 413 25 13 35
headquarters: Netherlands
Hycult Biotech develops, produces and markets antibodies, antibody based products and more specifically immunoassays for innate immunity and directly related fields, with an emphasis on complement, neutrophil proteins, TLR, scavenger receptors and acute phase proteins. Furthermore, we have a strong interest in progressing research in the area of inflammation and cell damage caused by pathogens or oxidation factors.

Hycult Biotech’s mission and strategy is to advance insight in innate immunity related diseases, for the benefit of individuals and their quality of life.

As a leader within focused fields of immunology and cell biology, we develop products for the life sciences and in accordance with our mission it is our ambition to facilitate the transition of these products from research use into diagnostic testing. Many of our reagents are developed in close cooperation with scientists worldwide. Hycult Biotech has built a strong network with over 40 close scientific collaborations with leading international research institutes. We contribute to numerous projects and as a result, can continuously offer early access to an expanding range of innovative reagents. Hycult Biotech has been ISO-9001 certified since 1998 and we upgraded our certification to ISO-13485 in 2007, with a milestone of our first release of CE marked assays in 2009. Our vision, knowledgeable team and quality management system guarantee products of the highest grade combined with excellent technical service.