product summary
company name :
Hycult Biotech
product type :
antibody
product name :
IFN-alpha, Mouse, mAb F18
catalog :
HM1001
quantity :
100 µg
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
F18
reactivity :
mouse
application :
immunoprecipitation, flow cytometry
more info or order :
Hycult Biotech product webpage
citations: 17
Reference
Khairoun M, van der Pol P, de Vries D, Lievers E, Schlagwein N, de Boer H, et al. Renal ischemia-reperfusion induces a dysbalance of angiopoietins, accompanied by proliferation of pericytes and fibrosis. Am J Physiol Renal Physiol. 2013;305:F901-10 pubmed publisher
Wikstrom M, Fleming P, Comerford I, McColl S, Andoniou C, Degli Esposti M. A chemokine-like viral protein enhances alpha interferon production by plasmacytoid dendritic cells but delays CD8+ T cell activation and impairs viral clearance. J Virol. 2013;87:7911-20 pubmed publisher
Geeraedts F, ter Veer W, Wilschut J, Huckriede A, de Haan A. Effect of viral membrane fusion activity on antibody induction by influenza H5N1 whole inactivated virus vaccine. Vaccine. 2012;30:6501-7 pubmed publisher
Davidson S, Kaiko G, Loh Z, Lalwani A, Zhang V, Spann K, et al. Plasmacytoid dendritic cells promote host defense against acute pneumovirus infection via the TLR7-MyD88-dependent signaling pathway. J Immunol. 2011;186:5938-48 pubmed publisher
Seeds R, Miller J. Measurement of type I interferon production. Curr Protoc Immunol. 2011;Chapter 14:Unit14.21.1-11 pubmed publisher
Hinson E, Joshi N, Chen J, Rahner C, Jung Y, Wang X, et al. Viperin is highly induced in neutrophils and macrophages during acute and chronic lymphocytic choriomeningitis virus infection. J Immunol. 2010;184:5723-31 pubmed publisher
Seeds R, Gordon S, Miller J. Characterisation of myeloid receptor expression and interferon alpha/beta production in murine plasmacytoid dendritic cells by flow cytomtery. J Immunol Methods. 2009;350:106-17 pubmed publisher
Iigo M, Alexander D, Long N, Xu J, Fukamachi K, Futakuchi M, et al. Anticarcinogenesis pathways activated by bovine lactoferrin in the murine small intestine. Biochimie. 2009;91:86-101 pubmed publisher
Rajsbaum R, Stoye J, O GARRA A. Type I interferon-dependent and -independent expression of tripartite motif proteins in immune cells. Eur J Immunol. 2008;38:619-30 pubmed publisher
Wang Z, Qiu J, Guo T, Liu A, Wang Y, Li Y, et al. Anti-inflammatory properties and regulatory mechanism of a novel derivative of artemisinin in experimental autoimmune encephalomyelitis. J Immunol. 2007;179:5958-65 pubmed
Boonstra A, Rajsbaum R, Holman M, Marques R, Asselin Paturel C, Pereira J, et al. Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals. J Immunol. 2006;177:7551-8 pubmed
Wang H, Peters N, Schwarze J. Plasmacytoid dendritic cells limit viral replication, pulmonary inflammation, and airway hyperresponsiveness in respiratory syncytial virus infection. J Immunol. 2006;177:6263-70 pubmed
Kato H, Sato S, Yoneyama M, Yamamoto M, Uematsu S, Matsui K, et al. Cell type-specific involvement of RIG-I in antiviral response. Immunity. 2005;23:19-28 pubmed
Feng H, Zhang D, Palliser D, Zhu P, Cai S, Schlesinger A, et al. Listeria-infected myeloid dendritic cells produce IFN-beta, priming T cell activation. J Immunol. 2005;175:421-32 pubmed
Asselin Paturel C, Brizard G, Chemin K, Boonstra A, O GARRA A, Vicari A, et al. Type I interferon dependence of plasmacytoid dendritic cell activation and migration. J Exp Med. 2005;201:1157-67 pubmed
Uematsu S, Sato S, Yamamoto M, Hirotani T, Kato H, Takeshita F, et al. Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction. J Exp Med. 2005;201:915-23 pubmed
Lund J, Sato A, Akira S, Medzhitov R, Iwasaki A. Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells. J Exp Med. 2003;198:513-20 pubmed
product information
Catalog no :
HM1001
Title :
IFN-alpha, Mouse, mAb F18
Clone no :
F18
Quantity :
100 µg
Application code :
flow cytometry,functional studies,immunoassays,immunoprecipitation
Species :
mouse
Host species :
rat
Isotype :
IgG1
Conjugate :
purified
Aliases :
IFN-alpha
Type :
mAb
Antigen :
IFN-alpha
Meta data :
IFN-alpha, interferon alpha
more info or order :
Hycult Biotech product webpage
company information
Hycult Biotech
Frontstraat 2a
5405 PB UDEN
support@hycultbiotech.com
www.hycultbiotech.com
31 0 413 25 13 35
headquarters: Netherlands
Hycult Biotech develops, produces and markets antibodies, antibody based products and more specifically immunoassays for innate immunity and directly related fields, with an emphasis on complement, neutrophil proteins, TLR, scavenger receptors and acute phase proteins. Furthermore, we have a strong interest in progressing research in the area of inflammation and cell damage caused by pathogens or oxidation factors.

Hycult Biotech’s mission and strategy is to advance insight in innate immunity related diseases, for the benefit of individuals and their quality of life.

As a leader within focused fields of immunology and cell biology, we develop products for the life sciences and in accordance with our mission it is our ambition to facilitate the transition of these products from research use into diagnostic testing. Many of our reagents are developed in close cooperation with scientists worldwide. Hycult Biotech has built a strong network with over 40 close scientific collaborations with leading international research institutes. We contribute to numerous projects and as a result, can continuously offer early access to an expanding range of innovative reagents. Hycult Biotech has been ISO-9001 certified since 1998 and we upgraded our certification to ISO-13485 in 2007, with a milestone of our first release of CE marked assays in 2009. Our vision, knowledgeable team and quality management system guarantee products of the highest grade combined with excellent technical service.