This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
CD4 antibody [AP-MAB0707]
catalog :
GTX85525
quantity :
100.00μg
price :
329 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
AP-MAB0707
reactivity :
mouse
application :
immunohistochemistry - paraffin section
product information
Catalog No :
GTX85525
Product Name :
CD4 antibody [AP-MAB0707]
Host Species :
Rat
Clonality :
Monoclonal
Product Type :
Primary antibody
Size :
100.00μg
List Price :
329 USD
Clone :
AP-MAB0707
Isotype :
IgG2
Product Description :
Rat Antibody [AP-MAB0707] to Mouse CD4
CrossReactivity :
Ms
Background :
T-cell surface glycoprotein CD4 (CD4) is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is reported that CD4 regulates T-cell activation and induces the aggregation of lipid rafts. CD4 associates with LCK, binds to HIV-1 gp120 and to P4HB/PDI, and upon HIV-1 binding to the cell membrane, it is part of the P4HB/PDI-CD4-CXCR4-gp120 complex. Cell surface expression of CD4 is down-modulated by HIV-1 Envelope polyprotein gp160, which interacts with and sequesters CD4 in the endoplasmic reticulum .
Immunogen :
Mouse CTL cells
Specificity :
mouse CD4
Buffer :
Phosphate Buffered Saline pH7.4
Uses :
FACS, IHC-P
Concentration :
0.5mg/ml
General References :
Store at -20 °C. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
company information
GeneTex
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