This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
ErbB2 antibody
catalog :
GTX85113
quantity :
100.00μg
price :
299 USD
clonality :
polyclonal
host :
chicken
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry
product information
Catalog No :
GTX85113
Product Name :
ErbB2 antibody
Host Species :
Chicken
Clonality :
Polyclonal
Product Type :
Primary antibody
Size :
100.00μg
List Price :
299 USD
Product Description :
Chicken polyclonal antibody to ErbB2
CrossReactivity :
Hu, Ms, Rat
Background :
The ErbB family consists of four closely related tyrosine kinase receptors that act as potent mediators of normal cell growth and development. Aberrant expression or function of one or more of these receptors can play a major role in the development and evolution of cancer. ErbB-2, also known as HER2, has been implicated in the evolution of both breast and gastric cancers, and is evident in other cancer types such as ovarian and salivary gland tumors. ErbB-2 possesses an active tyrosine kinase domain, but no direct ligand has been identified yet. ErbB-2 is the preferred binding partner to the other members of the ErbB family and is thought to act primarily through the Ras-MAPK, PI3k-PKB/Akt, and PLC-PKC signaling pathways. Numerous anti-cancer strategies have been employed against erbB-2, such as antibody-based therapies to prevent ligand binding or receptor activation through dimerization, antibody-dependent cell mediated cytotoxicity, in addition to direct kinase inhibition to prevent molecular activation/downstream signaling.
Immunogen :
erbB-2 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human erbB-2.
Specificity :
This antibody is specific for erbB-2
Buffer :
Antibody is supplied in PBS containing 0.02% sodium azide
Uses :
ELISA, IHC, WB
General References :
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
company information
GeneTex
2456 Alton Pkwy
Irvine, CA92606
info@genetex.com
www.genetex.com
1-877-436-3839
headquarters: USA