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product summary
company name :
GeneTex
product type :
antibody
product name :
Actin antibody [BA3R]
catalog :
GTX82559
quantity :
100.00μg
price :
289 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
BA3R
reactivity :
human, mouse, rat, chicken
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
product information
Catalog No :
GTX82559
Product Name :
Actin antibody [BA3R]
Host Species :
Mouse
Clonality :
Monoclonal
Product Type :
Primary antibody
Size :
100.00μg
List Price :
289 USD
Clone :
BA3R
Isotype :
IgG2b
Product Description :
Mouse monoclonal antibody [BA3R] to Actin
CrossReactivity :
Hu, Ms, Chk, Rat, Rb
Background :
Actin is a ubiquitous globular protein that is one of the most highly-conserved proteins known. It is found in two main states; G-actin is the globular monomeric form, whereas F-actin forms helical polymers. Both G- and F-actin are intrinsically flexible structures - a feature vital in actin's role as a dynamic filament network. Actin has four major functions. Firstly, F-actin polymers form microfilaments - polar intracellular 'tracks' for kinesin motor proteins, allowing the transport of vesicles, organelles and other cargo. Actin is a component of the cytoskeleton and links to alpha-actinin, E-cadherin and beta-catenin at adherens junctions. This gives mechanical support to cells and attaches them to each other and the extracellular matrix. In muscle cells, actin-rich thin filaments associate with myosin-rich thick filaments to form actomyosin myofibrils. Using energy from the hydrolysis of ATP, myofibrils undergo cyclic shortening through actin-myosin head interactions, which represents the mechanics of muscle contraction. Finally, actin has a role in cell motility through polymerization and depolymerization of fibrils.
Immunogen :
β-Actin N-terminal peptide-KLH conjugates
Specificity :
Recognizes native and denatured forms of β-Actin (∼42kDa)
Buffer :
10mM PBS, pH 7.2
Uses :
ELISA, ICC/IF, IHC, WB
Concentration :
1mg/ml
General References :
Store at 4°C (add 0.1% NaN3) for several days to weeks, and at -20°C for longer periods. Avoid repeated freeze-thaw cycles
company information
GeneTex
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