This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
CD45RB antibody [MEM-55] (APC)
catalog :
GTX78298
quantity :
100.00 test
price :
289 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
MEM-55
reactivity :
human
application :
western blot, immunohistochemistry, FACS
product information
Catalog No :
GTX78298
Product Name :
CD45RB antibody [MEM-55] (APC)
Host Species :
Mouse
Clonality :
Monoclonal
Conjugation :
APC
Product Type :
Primary antibody
Size :
100.00 test
List Price :
289 USD
Clone :
MEM-55
Isotype :
IgG1
Product Description :
Monoclonal Antibody to CD45RB (Human) Allophycocyanin (APC) conjugated
CrossReactivity :
Hu
Background :
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq]
Immunogen :
Human thymocytes and T lymphocytes.
Specificity :
The antibody recognizes a siliadase-sensitive epitope of CD45RB antigen.
Buffer :
The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
Uses :
FACS, IHC, WB
General References :
Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. Keep protected from prolonged exposure to light.
company information
GeneTex
questions and comments