HNF1 beta antibody | GeneTex GTX77876 product information

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product summary

company name :

GeneTex

product type :

antibody

product name :

HNF1 beta antibody

catalog :

GTX77876

quantity :

50.00μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

product information

Catalog No :

GTX77876

Product Name :

HNF1 beta antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary antibody

Size :

50.00μg

Isotype :

IgG

Product Description :

Rabbit Polyclonal Antibody to Hepatocyte Nuclear Factor 1- (TCF2)

CrossReactivity :

Background :

Hepatocyte Nuclear Factor 1- (HNF-1 , Homeoprotein LFB3, Transcription factor 2, TCF2, Variant hepatic nuclear factor ) is a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The TCF2 protein is believed to form heterodimers with another liver-specific member of this transcription factor family, TCF1; depending on the TCF2 isoform, the result may be to activate or inhibit transcription of target genes. Mutation of TCF2 that disrupts normal function has been identified as the cause of MODY5 (Maturity-Onset of Diabetes, Type 5). A third human transcript variant is believed to exist based on such a variant in the rat: however, to date such an mRNA species has not been isolated.

Immunogen :

Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of human TCF2

Buffer :

PBS with 2% sucrose

Uses :

Concentration :

1mg/ml

General References :

Store at -20 °C or below. Avoid repeat freeze-thaw cycles.