Hemoglobin antibody | GeneTex GTX77484 product information

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product summary

company name :

GeneTex

product type :

antibody

product name :

Hemoglobin antibody

catalog :

GTX77484

quantity :

1.00 mg

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA

product information

Catalog No :

GTX77484

Product Name :

Hemoglobin antibody

Host Species :

Goat

Clonality :

Polyclonal

Product Type :

Primary antibody

Size :

1.00 mg

list of Pubmed id :

20440295

Product Description :

Goat polyclonal to human hemoglobin

CrossReactivity :

Background :

The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5 - zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3 . The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5 untranslated regions and the introns, but they differ significantly over the 3 untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. [provided by RefSeq]

Immunogen :

Goats were immunized with human hemoglobin in Freund's adjuvant. After multiple immunizations the goats were bled, serum collected and the anti hemoglobin immunoaffinity purified.

Specificity :

GTX77484 forms a single precipitin band with human adult hemoglobin A1, A2, F and S, by immunoelectrophoresis.

Buffer :

Phosphate-buffered saline, pH 7.2, containing 0.1% sodium azide

Uses :

ELISA, WB

Concentration :

1mg/ml

General References :

Keep as concentrated solution, aliquot and store at 4°C.