Macrophage + Monocytes antibody [MAC387] | GeneTex GTX76577 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

Macrophage + Monocytes antibody [MAC387]

catalog :

GTX76577

quantity :

100.00μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MAC387

reactivity :

human, rat, dogs

application :

immunohistochemistry, FACS, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 1:500	Iigo M, Alexander D, Xu J, Futakuchi M, Suzui M, Kozu T, et al. Inhibition of intestinal polyp growth by oral ingestion of bovine lactoferrin and immune cells in the large intestine. Biometals. 2014;27:1017-29 pubmed publisher
	Lagumersindez Denis N, Wrzos C, Mack M, Winkler A, van der Meer F, Reinert M, et al. Differential contribution of immune effector mechanisms to cortical demyelination in multiple sclerosis. Acta Neuropathol. 2017;134:15-34 pubmed publisher
	Feng P, Lee K, Chang Y, Chan Y, Kuo L, Lin T, et al. CD14(+)S100A9(+) monocytic myeloid-derived suppressor cells and their clinical relevance in non-small cell lung cancer. Am J Respir Crit Care Med. 2012;186:1025-36 pubmed publisher

product information

Catalog No :

GTX76577

Product Name :

Macrophage + Monocytes antibody [MAC387]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

100.00μg

list of Pubmed id :

22955317

Clone :

MAC387

Isotype :

IgG1

Product Description :

Mouse monoclonal antibody [MAC387] to Macrophage + Monocyte

CrossReactivity :

Hu, Dog, Pig, Rat, Bb, Cat, Deer, Goat, Gpig, Hrs, Rb, Bov, RMK, ClMK

Background :

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis. [provided by RefSeq, Jul 2008]

Specificity :

The antigen recognized by clone MCA387 is expressed by granulocytes, monocytes and by tissue macrophages. Variable results have been reported for staining brain macrophages and microglia.

Buffer :

Phosphate buffered saline containing 0.09% Sodium Azide

Uses :

FACS, IHC, IHC-Fr, IHC-P

General References :

Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.