p15 INK4b antibody [DCS114.1] | GeneTex GTX75687 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

p15 INK4b antibody [DCS114.1]

catalog :

GTX75687

quantity :

50.00μg

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

DCS-114.1

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - frozen section

citations: 1

Reference
Sakellariou S, Liakakos T, Ghiconti I, Hadjikokolis S, Nakopoulou L, Pavlakis K. Immunohistochemical expression of P15 (INK4B) and SMAD4 in advanced gastric cancer. Anticancer Res. 2008;28:1079-83 pubmed

product information

Catalog No :

GTX75687

Product Name :

p15 INK4b antibody [DCS114.1]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

50.00μg

List Price :

359 USD

list of Pubmed id :

18507057

Clone :

DCS-114.1

Isotype :

IgG1

Product Description :

Mouse monoclonal antibody [DCS-114.1] to p15 INK4b

CrossReactivity :

Background :

This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]

Immunogen :

Full length recombinant p15 INK4b

Specificity :

This antibody recognizes human p15 INK4b.

Buffer :

Phosphate buffered saline containing 0.08% Sodium Azide

Uses :

IHC, IHC-Fr, IP, WB

General References :

Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.