MUC1 antibody [C595 (NCRC48)] (FITC) | GeneTex GTX75307 product information

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product summary

company name :

GeneTex

product type :

antibody

product name :

MUC1 antibody [C595 (NCRC48)] (FITC)

catalog :

GTX75307

quantity :

100.00μg

price :

329 USD

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

C595

reactivity :

human

application :

immunocytochemistry, FACS

product information

Catalog No :

GTX75307

Product Name :

MUC1 antibody [C595 (NCRC48)] (FITC)

Host Species :

Mouse

Clonality :

Monoclonal

Conjugation :

FITC

Product Type :

Primary antibody

Size :

100.00μg

List Price :

329 USD

Clone :

C595 (NCRC48)

Isotype :

IgG3

Product Description :

Mouse monoclonal antibody [C595 (NCRC48)] to MUC1

CrossReactivity :

Background :

This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]

Immunogen :

Urinary MUC-1 mucin.

Specificity :

This antibody recognizes the peptide epitope ARG-PRO-ALA-PRO within the protein core of the mucin.

Buffer :

Phosphate buffered saline containing 0.09% Sodium Azide 1% Bovine Serum Albumin

Uses :

FACS, ICC/IF

General References :

Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.