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product summary
company name :
GeneTex
product type :
antibody
product name :
CD45RB antibody [MEM-55]
catalog :
GTX74645
quantity :
200.00μg
price :
329 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MEM-55
reactivity :
human
application :
immunoprecipitation, FACS, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
Catalog No :
GTX74645
Product Name :
CD45RB antibody [MEM-55]
Host Species :
Mouse
Clonality :
Monoclonal
Product Type :
Primary antibody
Size :
200.00μg
List Price :
329 USD
Clone :
MEM-55
Isotype :
IgG1
Product Description :
Mouse monoclonal antibody [MEM-55] to CD45RB
CrossReactivity :
Hu, Mk, Rb, RMK
Background :
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
Specificity :
This antibody recognizes the isoform of CD45 encoded by exon B. Clone MEM-55 immunoprecipitates bands of 190, 200 and 205kD.
Buffer :
Phosphate buffered saline containing 0.09% Sodium Azide
Uses :
FACS, IHC-Fr, IHC-P, IP
General References :
Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
company information
GeneTex
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