IL1 beta antibody | GeneTex GTX74034 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

IL1 beta antibody

catalog :

GTX74034

quantity :

100.00μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry - frozen section

citations: 10

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; loading ...; fig 1c western blot; mouse; 1:1000; loading ...; fig s1g	Ising C, Venegas C, Zhang S, Scheiblich H, Schmidt S, Vieira Saecker A, et al. NLRP3 inflammasome activation drives tau pathology. Nature. 2019;: pubmed publisher
western blot; mouse; 1:3000; loading ...; fig s1a	Van Gorp H, Saavedra P, de Vasconcelos N, Van Opdenbosch N, Vande Walle L, Matusiak M, et al. Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation. Proc Natl Acad Sci U S A. 2016;113:14384-14389 pubmed
western blot; mouse; loading ...; fig 2a	Zanoni I, Tan Y, Di Gioia M, Broggi A, Ruan J, Shi J, et al. An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells. Science. 2016;352:1232-6 pubmed publisher
	Hafner Bratkovic I, Sušjan P, Lainšček D, Tapia Abellán A, Cerović K, Kadunc L, et al. NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway. Nat Commun. 2018;9:5182 pubmed publisher
	Ravussin A, Youm Y, Sander J, Ryu S, Nguyen K, Varela L, et al. Loss of Nucleobindin-2 Causes Insulin Resistance in Obesity without Impacting Satiety or Adiposity. Cell Rep. 2018;24:1085-1092.e6 pubmed publisher
	Kanneganti A, Malireddi R, Saavedra P, Vande Walle L, Van Gorp H, Kambara H, et al. GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever. J Exp Med. 2018;215:1519-1529 pubmed publisher
	Lee B, Mirrashidi K, Stowe I, Kummerfeld S, Watanabe C, Haley B, et al. ASC- and caspase-8-dependent apoptotic pathway diverges from the NLRC4 inflammasome in macrophages. Sci Rep. 2018;8:3788 pubmed publisher
	Van Opdenbosch N, Van Gorp H, Verdonckt M, Saavedra P, de Vasconcelos N, Gonçalves A, et al. Caspase-1 Engagement and TLR-Induced c-FLIP Expression Suppress ASC/Caspase-8-Dependent Apoptosis by Inflammasome Sensors NLRP1b and NLRC4. Cell Rep. 2017;21:3427-3444 pubmed publisher
	Qu Y, Misaghi S, Newton K, Maltzman A, Izrael Tomasevic A, Arnott D, et al. NLRP3 recruitment by NLRC4 during Salmonella infection. J Exp Med. 2016;213:877-85 pubmed publisher
	Van Opdenbosch N, Gurung P, Vande Walle L, Fossoul A, Kanneganti T, Lamkanfi M. Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation. Nat Commun. 2014;5:3209 pubmed publisher

product information

Catalog No :

GTX74034

Product Name :

IL1 beta antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Product Type :

Primary antibody

Size :

100.00μg

list of Pubmed id :

22002608,25043000,25156732,25686106

Isotype :

IgG

Product Description :

Rabbit polyclonal antibody to IL1 beta

CrossReactivity :

Immunogen :

Recombinant murine IL1 beta

Specificity :

This antibody recognizes mouse Interleukin-1 beta (IL1 beta).

Buffer :

Phosphate buffered saline

Uses :

ELISA, IHC-Fr, WB, Functional Assay

General References :

Prior to reconstitution store at +4°C. Following reconstitution store at -20°C. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.