Rad52 antibody [5H9] | GeneTex GTX70301 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

Rad52 antibody [5H9]

catalog :

GTX70301

quantity :

100.00μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5H9

reactivity :

human

application :

western blot

citations: 4

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:200; loading ...; fig 2a	Wang Y, Deng O, Feng Z, Du Z, Xiong X, Lai J, et al. RNF126 promotes homologous recombination via regulation of E2F1-mediated BRCA1 expression. Oncogene. 2016;35:1363-72 pubmed publisher
	Momcilovic O, Knobloch L, Fornsaglio J, Varum S, Easley C, Schatten G. DNA damage responses in human induced pluripotent stem cells and embryonic stem cells. PLoS ONE. 2010;5:e13410 pubmed publisher
	de Souza Pinto N, Maynard S, Hashiguchi K, Hu J, Muftuoglu M, Bohr V. The recombination protein RAD52 cooperates with the excision repair protein OGG1 for the repair of oxidative lesions in mammalian cells. Mol Cell Biol. 2009;29:4441-54 pubmed publisher
	Crosby M, Kulshreshtha R, Ivan M, Glazer P. MicroRNA regulation of DNA repair gene expression in hypoxic stress. Cancer Res. 2009;69:1221-9 pubmed publisher

product information

Catalog No :

GTX70301

Product Name :

Rad52 antibody [5H9]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

100.00μg

list of Pubmed id :

19506022,19141645,20976220

Clone :

5H9

Isotype :

IgG1

Product Description :

Mouse monoclonal antibody [5H9] to Rad52

CrossReactivity :

Background :

DNA double-strand breaks can be generated by exposure to ionizing radiation or through endogenous cellular reactions. Double-strand breaks are generally thought to be repaired via one of two distinct mechanisms: homologous recombination (HR) or non-homologous end joining (NHEJ). Homologous recombination requires the activity of the members of the RAD52 epistasis group, which includeRAD50, RAD51, RAD52, RAD54, RDH54/TID1, RAD55, RAD57, RAD59, MRE11, and XRS2. RAD52 can catalyze strand annealing reactions, and can form oligomers that attach to ends of single-stranded DNA.

Immunogen :

Human Rad52 recombinant protein expressed in E. coli.

Buffer :

Phosphate-buffered saline, pH 7.2, containing no preservatives

Uses :

Concentration :

1mg/ml

General References :

Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.