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product summary
company name :
GeneTex
product type :
antibody
product name :
Rad51 antibody [13E4]
catalog :
GTX70296
quantity :
100.00μg
price :
299 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
13E4
reactivity :
human
application :
western blot
product information
Catalog No :
GTX70296
Product Name :
Rad51 antibody [13E4]
Host Species :
Mouse
Clonality :
Monoclonal
Product Type :
Primary antibody
Size :
100.00μg
List Price :
299 USD
Clone :
13E4
Isotype :
IgG1
Product Description :
Mouse monoclonal antibody to human Rad51
CrossReactivity :
Hu
Background :
Rad51, a 37 kDa protein, is the human homologue of E. coli RecA protein and a member of the RAD52 epistasis group in S. cerevisiae. In recent studies it has been reported that BRCA1 interacts with Rad51 and disease-causing mutations have been found in the BRCA1 region necessary for BRCA1/Rad51 interaction, implying that this interaction is important for tumor suppression. BRCA2 and Rad51 have also been shown to interact by direct binding of the BRC repeats located within exon 11 of BRCA2. When these repeats are deleted, the interaction is lost and cells become hypersensitive to the DNA damage caused by methyl methanesulfonate (MMS).
Immunogen :
Recombinant human Rad51 protein.
Buffer :
Phosphate-buffered saline, pH 7.2, containing no preservatives
Uses :
WB
Concentration :
1mg/ml
General References :
Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.
company information
GeneTex
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