Chk2 antibody [8F12] | GeneTex GTX70295 product information

product summary

company name :

GeneTex

product type :

antibody

product name :

Chk2 antibody [8F12]

catalog :

GTX70295

quantity :

100.00μg

price :

299 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8F12

reactivity :

human

application :

western blot, immunocytochemistry

more info or order :

GeneTex product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 2d	Lee J, Mand M, Kao C, Zhou Y, Ryu S, Richards A, et al. ATM directs DNA damage responses and proteostasis via genetically separable pathways. Sci Signal. 2018;11: pubmed publisher
western blot; human	Lee J, Guo Z, Myler L, Zheng S, Paull T. Direct activation of ATM by resveratrol under oxidizing conditions. PLoS ONE. 2014;9:e97969 pubmed publisher
	Chen H, Chang F, Hsieh Y, Cheng Y, Hsieh K, Tsai L, et al. A novel synthetic protoapigenone analogue, WYC02-9, induces DNA damage and apoptosis in DU145 prostate cancer cells through generation of reactive oxygen species. Free Radic Biol Med. 2011;50:1151-62 pubmed publisher

product information

Catalog No :

GTX70295

Product Name :

Chk2 antibody [8F12]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

100.00μg

List Price :

299 USD

list of Pubmed id :

21256211,24933654

Clone :

8F12

Isotype :

IgG

Product Description :

Mouse monoclonal antibody [8F12] to Chk2

CrossReactivity :

Background :

CHK2 controls cell cycle checkpoint and may participate in transduction of the DNA damage and replicational stress signals. CHK2 belongs to the Ser/Thr protein kinase family and its kinase actibity is up-regulated by autophosphorylation, It is phosphorylated rapidly in response to DNA damage and to replication block.

Immunogen :

Recombinant CHK2 protein

Specificity :

GTX70295 is specific for human CHK2 protein.

Buffer :

Phosphate-buffered saline, pH 7.2, containing no preservatives

Uses :

ICC/IF, WB

Concentration :

1mg/ml

General References :

Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.

more info or order :

GeneTex product webpage