GPX7 antibody [2704] | GeneTex GTX70266 product information

product summary

company name :

GeneTex

product type :

antibody

product name :

GPX7 antibody [2704]

catalog :

GTX70266

quantity :

100.00μg

price :

299 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2704

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section, western blot knockout validation

more info or order :

GeneTex product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; human; fig 2a western blot; human; fig 2a western blot knockout validation; mouse; fig 7c	Chen P, Weng J, Hsu P, Shew J, Huang Y, Lee W. NPGPx modulates CPEB2-controlled HIF-1α RNA translation in response to oxidative stress. Nucleic Acids Res. 2015;43:9393-404 pubmed publisher
western blot; human; fig 1	Wei P, Lo W, Su M, Shew J, Lee W. Non-targeting siRNA induces NPGPx expression to cooperate with exoribonuclease XRN2 for releasing the stress. Nucleic Acids Res. 2012;40:323-32 pubmed publisher
	Wei P, Wang Z, Lo W, Su M, Shew J, Chang T, et al. A cis-element with mixed G-quadruplex structure of NPGPx promoter is essential for nucleolin-mediated transactivation on non-targeting siRNA stress. Nucleic Acids Res. 2013;41:1533-43 pubmed publisher
	Peng D, Razvi M, Chen H, Washington K, Roessner A, Schneider-Stock R, et al. DNA hypermethylation regulates the expression of members of the Mu-class glutathione S-transferases and glutathione peroxidases in Barrett's adenocarcinoma. Gut. 2009;58:5-15 pubmed publisher
	Wei P, Hsieh Y, Su M, Jiang X, Hsu P, Lo W, et al. Loss of the oxidative stress sensor NPGPx compromises GRP78 chaperone activity and induces systemic disease. Mol Cell. 2012;48:747-59 pubmed publisher
	Utomo A, Jiang X, Furuta S, Yun J, Levin D, Wang Y, et al. Identification of a novel putative non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase (NPGPx) essential for alleviating oxidative stress generated from polyunsaturated fatty acids in breast cancer cells. J Biol Chem. 2004;279:43522-9 pubmed

product information

Catalog No :

GTX70266

Product Name :

GPX7 antibody [2704]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

100.00μg

List Price :

299 USD

list of Pubmed id :

23241391,23123197,15294905,21908404,18664505

Clone :

2704

Isotype :

IgG

Product Description :

Mouse monoclonal antibody [2704] to GPX7

CrossReactivity :

Background :

Human GPX7 (also known as glutathione peroxidase 6) is believed to be a member of the glutathione peroxidase family of proteins. These proteins play important roles in cellular defense mechanisms against oxidative damage. This is a ccomplished by catalyzing the reduction of hydroperoxides and hydrogen peroxide through the reducing substrate, glutathione.

Immunogen :

Human NPGPx

Buffer :

Phosphate-buffered saline, pH 7.4 containing no preservatives

Uses :

IHC, IHC-P, WB

Concentration :

1mg/ml

General References :

Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid freeze-thaw cycles.

more info or order :

GeneTex product webpage