This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
GeneTex
product type :
antibody
product name :
Estrogen Receptor alpha antibody [1F3]
catalog :
GTX70171
quantity :
100.00μg
price :
299 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1F3
reactivity :
human
application :
western blot, immunoprecipitation, FACS, immunohistochemistry - frozen section
citations: 3
Reference
Srilatha B, Adaikan P. Estrogen and phytoestrogen predispose to erectile dysfunction: do ER-alpha and ER-beta in the cavernosum play a role?. Urology. 2004;63:382-6 pubmed
Sun M, Estrov Z, Ji Y, Coombes K, Harris D, Kurzrock R. Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells. Mol Cancer Ther. 2008;7:464-73 pubmed publisher
Ivanova M, Mazhawidza W, Dougherty S, Minna J, Klinge C. Activity and intracellular location of estrogen receptors alpha and beta in human bronchial epithelial cells. Mol Cell Endocrinol. 2009;305:12-21 pubmed publisher
product information
Catalog No :
GTX70171
Product Name :
Estrogen Receptor alpha antibody [1F3]
Host Species :
Mouse
Clonality :
Monoclonal
Product Type :
Primary antibody
Size :
100.00μg
List Price :
299 USD
list of Pubmed id :
19433257,18347134,14972507
Clone :
1F3
Isotype :
IgG1
Product Description :
Mouse Monoclonal antibody [1F3] to Estrogen Receptor alpha
CrossReactivity :
Hu, Rb
Background :
The Estrogen Receptor (ER) is a 65a protein and a member of the steroid family of nuclear receptors. ER is a ligand-activated transcription factor and, when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) sequences. When bound to DNA, ER can positively or negatively regulate gene transcription through the recruitment of coactivator (e.g. SRC-1) or corepressor (e.g. NCoR) proteins.
Immunogen :
The region encoding amino acids 1-190 expressed in E. coli.
Buffer :
Phosphate-buffered saline, pH 7.4, containing no preservatives
Uses :
FACS, IHC-Fr, IP, WB
Concentration :
2.61mg/ml
General References :
Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.
company information
GeneTex
2456 Alton Pkwy
Irvine, CA92606
info@genetex.com
www.genetex.com
1-877-436-3839
headquarters: USA