BRCA2 antibody [5F6] | GeneTex GTX70123 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

BRCA2 antibody [5F6]

catalog :

GTX70123

quantity :

100.00μg

price :

299 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5F6

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 3

Reference
Bernard-Gallon D, Dechelotte P, Le Corre L, Chalabi N, Vissac-Sabatier C, Bignon Y. Differential expressions of BRCA1 and BRCA2 in infantile gynecomastia. Anticancer Res. 2004;24:321-4 pubmed
Bosviel R, Dumollard E, Dechelotte P, Bignon Y, Bernard-Gallon D. Can soy phytoestrogens decrease DNA methylation in BRCA1 and BRCA2 oncosuppressor genes in breast cancer?. OMICS. 2012;16:235-44 pubmed publisher
Bernard-Gallon D, Vissac C, Aunoble B, Cravello L, Malpuech G, Bignon Y. BRCA1 and BRCA2 protein expressions in an ovotestis of a 46, XX true hermaphrodite. Breast Cancer Res. 2001;3:61-5 pubmed

product information

Catalog No :

GTX70123

Product Name :

BRCA2 antibody [5F6]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

100.00μg

List Price :

299 USD

list of Pubmed id :

15015615,11250747,22339411

Clone :

5F6

Isotype :

IgG1

Product Description :

Mouse monoclonal [5F6] to BRCA2

CrossReactivity :

Background :

BRCA2-5F6 recognizes the BRCA2 gene product, a 390kDa nuclear protein. The BRCA2 gene was originally isolated based on its importance in the predisposition of women to early-onset breast and ovarian cancers, suggesting mutations affect its tumor suppressor-like activity. Targeted disruption of the BRCA2 gene in mice and binding of Rad51 to its carboxyl terminus have indicated an involvement in DNA recombination and double strand break repair.

Immunogen :

Amino acids 2336-2478 of human BRCA2 expressed in E. coli. BRCA2-P400.

Buffer :

Phosphate-buffered saline, pH 7.2, no preservative added.

Uses :

IHC, IHC-Fr, IHC-P, WB

Concentration :

1mg/ml

General References :

Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.