BRCA2 antibody [9D3] | GeneTex GTX70119 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

BRCA2 antibody [9D3]

catalog :

GTX70119

quantity :

100.00μg

price :

299 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9D3

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 2

Reference
Wu K, Jiang S, Thangaraju M, Wu G, Couch F. Induction of the BRCA2 promoter by nuclear factor-kappa B. J Biol Chem. 2000;275:35548-56 pubmed
Bernard-Gallon D, Dechelotte P, Le Corre L, Chalabi N, Vissac-Sabatier C, Bignon Y. Differential expressions of BRCA1 and BRCA2 in infantile gynecomastia. Anticancer Res. 2004;24:321-4 pubmed

product information

Catalog No :

GTX70119

Product Name :

BRCA2 antibody [9D3]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary antibody

Size :

100.00μg

List Price :

299 USD

list of Pubmed id :

10961992,15015615

Clone :

9D3

Isotype :

IgG1

Product Description :

Mouse monoclonal [9D3] to BRCA2

CrossReactivity :

Background :

BRCA2-9D3 recognizes the BRCA2 gene product, a 390kDa nuclear protein. The BRCA2 gene was originally isolated based on its importance in the predisposition of women to early-onset breast and ovarian cancers, suggesting mutations affect its tumor suppressor-like activity. Targeted disruption of the BRCA2 gene in mice and binding of Rad51 to its carboxyl terminus have indicated an involvement in DNA recombination and double strand break repair.

Immunogen :

BRCA2 protein fragment containing amino acids 2336-2478 of human BRCA2 expressed in E. coli. BRCA2-P400.

Specificity :

This antibody recognizes BRCA2, a 390-kDa nuclear protein.

Buffer :

Phosphate-buffered saline, pH 7.2, no preservative added.

Uses :

IHC, IHC-P, IP, WB

Concentration :

1mg/ml

General References :

Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid freeze-thaw cycles.