beta Catenin antibody [GT2169] | GeneTex GTX633010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

beta Catenin antibody [GT2169]

catalog :

GTX633010

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

GTX633010

Product Name :

beta Catenin antibody [GT2169]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary Antibody

Background :

Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the 'contact inhibition' signal, which instructs cells to stop dividing once an epithelial sheet is complete.[supplied by OMIM]