T-Plastin antibody [GT3310] | GeneTex GTX632482 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

T-Plastin antibody [GT3310]

catalog :

GTX632482

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human

citations: 1

Reference
Schenk L, MÃ¶ller Kerutt A, Klosowski R, Wolters D, Schaffner Reckinger E, Weide T, et al. Angiotensin II regulates phosphorylation of actin-associated proteins in human podocytes. FASEB J. 2017;31:5019-5035 pubmed publisher

product information

Catalog Number :

GTX632482

Product Name :

T-Plastin antibody [GT3310]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary Antibody

list of Pubmed id :

28768720

Background :

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]