T-Plastin antibody [GT236] | GeneTex GTX632481 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

T-Plastin antibody [GT236]

catalog :

GTX632481

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

GTX632481

Product Name :

T-Plastin antibody [GT236]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary Antibody

Background :

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]