product summary
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company name :
GeneTex
product type :
antibody
product name :
alpha Tubulin antibody [GT114]
catalog :
GTX628802
quantity :
100.00μl
price :
299 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
GT114
reactivity :
human, mouse, zebrafish
application :
western blot, immunocytochemistry, chromatin immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 16
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 2a
Choe K, Nicolae C, Constantin D, Imamura Kawasawa Y, Delgado Diaz M, De S, et al. HUWE1 interacts with PCNA to alleviate replication stress. EMBO Rep. 2016;17:874-86 pubmed publisher
  • chromatin immunoprecipitation; zebrafish ; 1:2000
Lin T, Chou C, Chung H, Chiang C, Li C, Wu J, et al. Hypoxia-inducible factor 2 alpha is essential for hepatic outgrowth and functions via the regulation of leg1 transcription in the zebrafish embryo. PLoS ONE. 2014;9:e101980 pubmed publisher
Kikuma K, Li X, Perry S, Li Q, Goel P, Chen C, et al. Cul3 and insomniac are required for rapid ubiquitination of postsynaptic targets and retrograde homeostatic signaling. Nat Commun. 2019;10:2998 pubmed publisher
Ackermann T, Hartleben G, Muller C, Mastrobuoni G, Groth M, Sterken B, et al. C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7/LIN28B circuit in mice. Commun Biol. 2019;2:208 pubmed publisher
Teng L, Lu G, Chiou L, Lin W, Cheng Y, Hsueh T, et al. Serotonin receptor HTR6-mediated mTORC1 signaling regulates dietary restriction-induced memory enhancement. PLoS Biol. 2019;17:e2007097 pubmed publisher
Zhang D, Ma J. Mitochondrial Dynamics in Rat Heart Induced by 5-Fluorouracil. Med Sci Monit. 2018;24:6666-6672 pubmed publisher
Vorontsova I, Gehring I, Hall J, Schilling T. Aqp0a Regulates Suture Stability in the Zebrafish Lens. Invest Ophthalmol Vis Sci. 2018;59:2869-2879 pubmed publisher
Macdougall C, Wood E, Loschko J, Scagliotti V, Cassidy F, Robinson M, et al. Visceral Adipose Tissue Immune Homeostasis Is Regulated by the Crosstalk between Adipocytes and Dendritic Cell Subsets. Cell Metab. 2018;27:588-601.e4 pubmed publisher
Wilkie A, Sharma M, Pesola J, Ericsson M, Fernandez R, Coen D. A Role for Myosin Va in Human Cytomegalovirus Nuclear Egress. J Virol. 2018;92: pubmed publisher
Xiao X, Yang H, Arutiunian V, Fang Y, Besse G, Morimoto C, et al. Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation. Nucleic Acids Res. 2017;45:7494-7506 pubmed publisher
Gan Z, Ding L, Burckhardt C, Lowery J, Zaritsky A, Sitterley K, et al. Vimentin Intermediate Filaments Template Microtubule Networks to Enhance Persistence in Cell Polarity and Directed Migration. Cell Syst. 2016;3:252-263.e8 pubmed publisher
Naik N, Wu H. Mutation of Putative N-Glycosylation Sites on Dengue Virus NS4B Decreases RNA Replication. J Virol. 2015;89:6746-60 pubmed publisher
Li K, Hua K, Lin Y, Su C, Ko J, Hsiao M, et al. Inhibition of G9a induces DUSP4-dependent autophagic cell death in head and neck squamous cell carcinoma. Mol Cancer. 2014;13:172 pubmed publisher
Emhemmed F, Ali Azouaou S, Thuaud F, Schini Kerth V, Desaubry L, Muller C, et al. Selective anticancer effects of a synthetic flavagline on human Oct4-expressing cancer stem-like cells via a p38 MAPK-dependent caspase-3-dependent pathway. Biochem Pharmacol. 2014;89:185-96 pubmed publisher
Chu T, Liou A, Su P, Wu H, Shih C. Nucleic acid chaperone activity associated with the arginine-rich domain of human hepatitis B virus core protein. J Virol. 2014;88:2530-43 pubmed publisher
Eshima H, Tanaka Y, Sonobe T, Inagaki T, Nakajima T, Poole D, et al. In vivo imaging of intracellular Ca2+ after muscle contractions and direct Ca2+ injection in rat skeletal muscle in diabetes. Am J Physiol Regul Integr Comp Physiol. 2013;305:R610-8 pubmed publisher
product information
Catalog No :
GTX628802
Product Name :
alpha Tubulin antibody [GT114]
Host Species :
Mouse
Clonality :
Monoclonal
Product Type :
Primary antibody
Size :
100.00μl
List Price :
299 USD
list of Pubmed id :
24352445,23883681,24607276,25000307,25027955,25878113
Clone :
GT114
Isotype :
IgG2a
Product Description :
Mouse Monoclonal antibody [GT114] to alpha Tubulin (tubulin, alpha 1b)
CrossReactivity :
Hu, Ms, Dm, Rat, Zfsh
Background :
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
Immunogen :
Recombinant protein encompassing a sequence within the center region of human alpha Tubulin. The exact sequence is proprietary.
Buffer :
PBS
Uses :
ICC/IF, IHC-P, WB
Concentration :
1mg/ml
General References :
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Image Legend_4 :
alpha Tubulin antibody [GT114] detects TUBA1B protein by Western blot analysis. A. 30 µg zebrafish eye lysate/extract 10 % SDS-PAGE alpha Tubulin antibody [GT114] (GTX628802) dilution: 1:1000
Image Legend_5 :
TUBA1B antibody detects TUBA1B protein at Cytoskeleton by immunofluorescent analysis. Sample: HeLa cells were fixed in -20℃ 100% methanol for 5 min. Green: TUBA1B protein stained by TUBA1B antibody (GTX628802) diluted at 1:500. Blue: Hoechst 33342 staining.
Image Legend_6 :
alpha Tubulin antibody [GT114] detects alpha Tubulin protein at cytoplasm in human lung cancer by immunohistochemical analysis. Sample: Paraffin-embedded human lung cancer. alpha Tubulin antibody [GT114] (GTX628802) diluted at 1:500.
Image Legend_7 :
alpha Tubulin antibody [GT114] detects alpha Tubulin protein at cytoplasm in human cervix by immunohistochemical analysis. Sample: Paraffin-embedded human cervix. alpha Tubulin antibody [GT114] (GTX628802) diluted at 1:500.
Image Legend_8 :
alpha Tubulin antibody [GT114] detects alpha Tubulin protein at cytoskeleton by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: alpha Tubulin protein stained by alpha Tubulin antibody [GT114] (GTX628802) diluted at 1:1000. Blue: Hoechst 33342 staining. Scale bar = 10 μm.
more info or order :
company information
GeneTex
2456 Alton Pkwy
Irvine, CA92606
info@genetex.com
http://www.genetex.com
1-877-436-3839
headquarters: USA