CBS antibody [GT519] | GeneTex GTX628777 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

GeneTex

product type :

antibody

product name :

CBS antibody [GT519]

catalog :

GTX628777

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

GT519

reactivity :

human, mouse

application :

western blot

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; loading ...; fig 1b	Ahmad A, Gero D, Olah G, Szabo C. Effect of endotoxemia in mice genetically deficient in cystathionine-?-lyase, cystathionine-?-synthase or 3-mercaptopyruvate sulfurtransferase. Int J Mol Med. 2016;38:1683-1692 pubmed publisher
	Pincini A, Tornillo G, Orso F, Sciortino M, Bisaro B, Leal M, et al. Identification of p130Cas/ErbB2-dependent invasive signatures in transformed mammary epithelial cells. Cell Cycle. 2013;12:2409-22 pubmed publisher

product information

Catalog Number :

GTX628777

Product Name :

CBS antibody [GT519]

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary Antibody

list of Pubmed id :

27748832,23839042

Background :

The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. [provided by RefSeq]